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428 results

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Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study.
Mebazaa A, Geven C, Hollinger A, Wittebole X, Chousterman BG, Blet A, Gayat E, Hartmann O, Scigalla P, Struck J, Bergmann A, Antonelli M, Beishuizen A, Constantin JM, Damoisel C, Deye N, Di Somma S, Dugernier T, François B, Gaudry S, Huberlant V, Lascarrou JB, Marx G, Mercier E, Oueslati H, Pickkers P, Sonneville R, Legrand M, Laterre PF; AdrenOSS-1 study investigators. Mebazaa A, et al. Among authors: hartmann o. Crit Care. 2018 Dec 21;22(1):354. doi: 10.1186/s13054-018-2243-2. Crit Care. 2018. PMID: 30583748 Free PMC article.
Bioactive Adrenomedullin, Organ Support Therapies, and Survival in the Critically Ill: Results from the French and European Outcome Registry in ICU Study.
Lemasle L, Blet A, Geven C, Cherifa M, Deniau B, Hollinger A, Fournier MC, Monnet X, Rennuit I, Darmon M, Laterre PF, Struck J, Hartmann O, Bergmann A, Mebazaa A, Gayat E. Lemasle L, et al. Among authors: hartmann o. Crit Care Med. 2020 Jan;48(1):49-55. doi: 10.1097/CCM.0000000000004044. Crit Care Med. 2020. PMID: 31625979
Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study.
Blet A, Deniau B, Santos K, van Lier DPT, Azibani F, Wittebole X, Chousterman BG, Gayat E, Hartmann O, Struck J, Bergmann A, Antonelli M, Beishuizen A, Constantin JM, Damoisel C, Deye N, Di Somma S, Dugernier T, François B, Gaudry S, Huberlant V, Lascarrou JB, Marx G, Mercier E, Oueslati H, Pickkers P, Sonneville R, Legrand M, Laterre PF, Mebazaa A; AdrenOSS-1 Study Investigators. Blet A, et al. Among authors: hartmann o. Crit Care. 2021 Feb 15;25(1):61. doi: 10.1186/s13054-021-03471-2. Crit Care. 2021. PMID: 33588925 Free PMC article.
A double-blind, placebo-controlled, randomised, multicentre, proof-of-concept and dose-finding phase II clinical trial to investigate the safety, tolerability and efficacy of adrecizumab in patients with septic shock and elevated adrenomedullin concentration (AdrenOSS-2).
Geven C, Blet A, Kox M, Hartmann O, Scigalla P, Zimmermann J, Marx G, Laterre PF, Mebazaa A, Pickkers P. Geven C, et al. Among authors: hartmann o. BMJ Open. 2019 Feb 19;9(2):e024475. doi: 10.1136/bmjopen-2018-024475. BMJ Open. 2019. PMID: 30782906 Free PMC article.
Activity of the adrenomedullin system to personalise post-discharge diuretic treatment in acute heart failure.
Kozhuharov N, Ng L, Wussler D, Strebel I, Sabti Z, Hartmann O, Eltayeb M, Squire I, Nowak A, Rieger M, Martin J, Michou E, Stefanelli S, Puelacher C, Shrestha S, Belkin M, Zimmermann T, Lopez-Ayala P, Struck J, Bergmann A, Mebazaa A, Blet A, Gualandro DM, Breidthardt T, Mueller C. Kozhuharov N, et al. Among authors: hartmann o. Clin Res Cardiol. 2022 Jun;111(6):627-637. doi: 10.1007/s00392-021-01909-9. Epub 2021 Jul 23. Clin Res Cardiol. 2022. PMID: 34302189 Free PMC article.
Safety and tolerability of non-neutralizing adrenomedullin antibody adrecizumab (HAM8101) in septic shock patients: the AdrenOSS-2 phase 2a biomarker-guided trial.
Laterre PF, Pickkers P, Marx G, Wittebole X, Meziani F, Dugernier T, Huberlant V, Schuerholz T, François B, Lascarrou JB, Beishuizen A, Oueslati H, Contou D, Hoiting O, Lacherade JC, Chousterman B, Pottecher J, Bauer M, Godet T, Karakas M, Helms J, Bergmann A, Zimmermann J, Richter K, Hartmann O, Pars M, Mebazaa A; AdrenOSS-2 study participants. Laterre PF, et al. Among authors: hartmann o. Intensive Care Med. 2021 Nov;47(11):1284-1294. doi: 10.1007/s00134-021-06537-5. Epub 2021 Oct 4. Intensive Care Med. 2021. PMID: 34605947 Free PMC article. Clinical Trial.
PenKid measurement at admission is associated with outcome in severely ill burn patients.
Dépret F, Polina A, Amzallag J, Fayolle-Pivot L, Coutrot M, Chaussard M, Struck J, Hartmann O, Jully M, Fratani A, Oueslati H, Cupaciu A, Soussi S, Benyamina M, Guillemet L, Mebazaa A, Textoris J, Legrand M; PRONOBURN group. Dépret F, et al. Among authors: hartmann o. Burns. 2020 Sep;46(6):1302-1309. doi: 10.1016/j.burns.2020.01.002. Epub 2020 Jan 25. Burns. 2020. PMID: 31987659
Circulating dipeptidyl peptidase-3 at admission is associated with circulatory failure, acute kidney injury and death in severely ill burn patients.
Dépret F, Amzallag J, Pollina A, Fayolle-Pivot L, Coutrot M, Chaussard M, Santos K, Hartmann O, Jully M, Fratani A, Oueslati H, Cupaciu A, Benyamina M, Guillemet L, Deniau B, Mebazaa A, Gayat E, Farny B, Textoris J, Legrand M; PRONOBURN group. Dépret F, et al. Among authors: hartmann o. Crit Care. 2020 Apr 22;24(1):168. doi: 10.1186/s13054-020-02888-5. Crit Care. 2020. PMID: 32321571 Free PMC article.
428 results