Hamouda AK - Search Results

1

Advances in the In vitro and In vivo pharmacology of Alpha4beta2 nicotinic receptor positive allosteric modulators.

Wilkerson JL, Deba F, Crowley ML, Hamouda AK, McMahon LR. Wilkerson JL, et al. Among authors: hamouda ak. Neuropharmacology. 2020 May 15;168:108008. doi: 10.1016/j.neuropharm.2020.108008. Epub 2020 Feb 12. Neuropharmacology. 2020. PMID: 32113032 Free PMC article. Review.

2

Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)3(β2)2 nAChR-Selective Positive Allosteric Modulator.

Hamouda AK, Deba F, Wang ZJ, Cohen JB. Hamouda AK, et al. Mol Pharmacol. 2016 May;89(5):575-84. doi: 10.1124/mol.116.103341. Epub 2016 Mar 14. Mol Pharmacol. 2016. PMID: 26976945 Free PMC article.

3

Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2)2-type nicotinic acetylcholine receptor responses.

Wang ZJ, Deba F, Mohamed TS, Chiara DC, Ramos K, Hamouda AK. Wang ZJ, et al. Among authors: hamouda ak. J Biol Chem. 2017 Jun 16;292(24):9988-10001. doi: 10.1074/jbc.M116.771246. Epub 2017 Apr 26. J Biol Chem. 2017. PMID: 28446611 Free PMC article.

4

Reversal of Nicotine Withdrawal Signs Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Male Mice.

Hamouda AK, Jackson A, Bagdas D, Imad Damaj M. Hamouda AK, et al. Nicotine Tob Res. 2018 Jun 7;20(7):903-907. doi: 10.1093/ntr/ntx183. Nicotine Tob Res. 2018. PMID: 29059422 Free PMC article.

5

LY2087101 and dFBr share transmembrane binding sites in the (α4)3(β2)2 Nicotinic Acetylcholine Receptor.

Deba F, Ali HI, Tairu A, Ramos K, Ali J, Hamouda AK. Deba F, et al. Among authors: hamouda ak. Sci Rep. 2018 Jan 19;8(1):1249. doi: 10.1038/s41598-018-19790-4. Sci Rep. 2018. PMID: 29352227 Free PMC article.

6

An Animal Model to Test Reversal of Cognitive Decline Associated with Beta-Amyloid Pathologies.

Deba F, Peterson S, Hamouda AK. Deba F, et al. Among authors: hamouda ak. Methods Mol Biol. 2019;2011:393-412. doi: 10.1007/978-1-4939-9554-7_23. Methods Mol Biol. 2019. PMID: 31273712

7

Examining the Effects of (α4)3(β2)2 Nicotinic Acetylcholine Receptor-Selective Positive Allosteric Modulator on Acute Thermal Nociception in Rats.

Deba F, Ramos K, Vannoy M, Munoz K, Akinola LS, Damaj MI, Hamouda AK. Deba F, et al. Among authors: hamouda ak. Molecules. 2020 Jun 25;25(12):2923. doi: 10.3390/molecules25122923. Molecules. 2020. PMID: 32630476 Free PMC article.

8

Potentiation of (α4)2(β2)3, but not (α4)3(β2)2, nicotinic acetylcholine receptors reduces nicotine self-administration and withdrawal symptoms.

Hamouda AK, Bautista MR, Akinola LS, Alkhlaif Y, Jackson A, Carper M, Toma WB, Garai S, Chen YC, Thakur GA, Fowler CD, Damaj MI. Hamouda AK, et al. Neuropharmacology. 2021 Jun 1;190:108568. doi: 10.1016/j.neuropharm.2021.108568. Epub 2021 Apr 18. Neuropharmacology. 2021. PMID: 33878302 Free PMC article.

9

Assessing potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor by the allosteric agonist CMPI.

Deba F, Munoz K, Peredia E, Akk G, Hamouda AK. Deba F, et al. Among authors: hamouda ak. J Biol Chem. 2022 Jan;298(1):101455. doi: 10.1016/j.jbc.2021.101455. Epub 2021 Nov 30. J Biol Chem. 2022. PMID: 34861241 Free PMC article.

10

Pyrrolidinyl benzofurans and benzodioxanes: Selective α4β2 nicotinic acetylcholine receptor ligands with different activity profiles at the two receptor stoichiometries.

Appiani R, Pallavicini M, Hamouda AK, Bolchi C. Appiani R, et al. Among authors: hamouda ak. Bioorg Med Chem Lett. 2022 Jun 1;65:128701. doi: 10.1016/j.bmcl.2022.128701. Epub 2022 Mar 25. Bioorg Med Chem Lett. 2022. PMID: 35346843 Free article.

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