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Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development.
Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne EM, Durieux I, Ewart L, Fitzpatrick SC, Frey O, Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes DJ, Ingber DE, Iskandar A, Kanamori T, Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S, Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A. Marx U, et al. Among authors: david r. ALTEX. 2020;37(3):365-394. doi: 10.14573/altex.2001241. Epub 2020 Feb 28. ALTEX. 2020. PMID: 32113184 Free PMC article.
On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology.
Chou DB, Frismantas V, Milton Y, David R, Pop-Damkov P, Ferguson D, MacDonald A, Vargel Bölükbaşı Ö, Joyce CE, Moreira Teixeira LS, Rech A, Jiang A, Calamari E, Jalili-Firoozinezhad S, Furlong BA, O'Sullivan LR, Ng CF, Choe Y, Marquez S, Myers KC, Weinberg OK, Hasserjian RP, Novak R, Levy O, Prantil-Baun R, Novina CD, Shimamura A, Ewart L, Ingber DE. Chou DB, et al. Among authors: david r. Nat Biomed Eng. 2020 Apr;4(4):394-406. doi: 10.1038/s41551-019-0495-z. Epub 2020 Jan 27. Nat Biomed Eng. 2020. PMID: 31988457 Free PMC article.
Organ-on-a-chip: current gaps and future directions.
Candarlioglu PL, Dal Negro G, Hughes D, Balkwill F, Harris K, Screen H, Morgan H, David R, Beken S, Guenat O, Rowan W, Amour A. Candarlioglu PL, et al. Among authors: david r. Biochem Soc Trans. 2022 Apr 29;50(2):665-673. doi: 10.1042/BST20200661. Biochem Soc Trans. 2022. PMID: 35437569 Free PMC article.
Author Correction: On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology.
Chou DB, Frismantas V, Milton Y, David R, Pop-Damkov P, Ferguson D, MacDonald A, Vargel Bölükbaşı Ö, Joyce CE, Moreira Teixeira LS, Rech A, Jiang A, Calamari E, Jalili-Firoozinezhad S, Furlong BA, O'Sullivan LR, Ng CF, Choe Y, Marquez S, Myers KC, Weinberg OK, Hasserjian RP, Novak R, Levy O, Prantil-Baun R, Novina CD, Shimamura A, Ewart L, Ingber DE. Chou DB, et al. Among authors: david r. Nat Biomed Eng. 2020 Apr;4(4):477. doi: 10.1038/s41551-020-0529-6. Nat Biomed Eng. 2020. PMID: 32051581
Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors.
Chou DB, Furlong BA, Posey RR, Kyprianou C, O'Sullivan LR, David R, Randle SJ, Polanska UM, Travers J, Urosevic J, Hutchinson JN, Che J, Howley AM, Hasserjian RP, Prantil-Baun R, Ingber DE. Chou DB, et al. Among authors: david r. Nat Commun. 2022 Oct 12;13(1):6021. doi: 10.1038/s41467-022-33672-4. Nat Commun. 2022. PMID: 36224199 Free PMC article.
Considerations from an International Regulatory and Pharmaceutical Industry (IQ MPS Affiliate) Workshop on the Standardization of Complex In Vitro Models in Drug Development.
Tomlinson L, Ramsden D, Leite SB, Beken S, Bonzo JA, Brown P, Candarlioglu PL, Chan TS, Chen E, Choi CK, David R, Delrue N, Devine PJ, Ford K, Garcia MI, Gosset JR, Hewitt P, Homan K, Irrechukwu O, Kopec AK, Liras JL, Mandlekar S, Raczynski A, Sadrieh N, Sakatis MZ, Siegel J, Sung K, Sunyovszki I, Van Vleet TR, Ekert JE, Hardwick RN. Tomlinson L, et al. Among authors: david r. Adv Biol (Weinh). 2024 Aug;8(8):e2300131. doi: 10.1002/adbi.202300131. Epub 2023 Oct 9. Adv Biol (Weinh). 2024. PMID: 37814378
1,457 results