Wong CH - Search Results

1

Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis.

Jarosz-Griffiths HH, Scambler T, Wong CH, Lara-Reyna S, Holbrook J, Martinon F, Savic S, Whitaker P, Etherington C, Spoletini G, Clifton I, Mehta A, McDermott MF, Peckham D. Jarosz-Griffiths HH, et al. Among authors: wong ch. Elife. 2020 Mar 2;9:e54556. doi: 10.7554/eLife.54556. Elife. 2020. PMID: 32118580 Free PMC article.

2

Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients.

Gillespie J, Savic S, Wong C, Hempshall A, Inman M, Emery P, Grigg R, McDermott MF. Gillespie J, et al. Arthritis Rheum. 2012 Feb;64(2):418-22. doi: 10.1002/art.33382. Arthritis Rheum. 2012. PMID: 21952924 Free article.

3

Involvement of X-box binding protein 1 and reactive oxygen species pathways in the pathogenesis of tumour necrosis factor receptor-associated periodic syndrome.

Dickie LJ, Aziz AM, Savic S, Lucherini OM, Cantarini L, Geiler J, Wong CH, Coughlan R, Lane T, Lachmann HJ, Hawkins PN, Robinson PA, Emery P, McGonagle D, McDermott MF. Dickie LJ, et al. Among authors: wong ch. Ann Rheum Dis. 2012 Dec;71(12):2035-43. doi: 10.1136/annrheumdis-2011-201197. Epub 2012 Jun 7. Ann Rheum Dis. 2012. PMID: 22679299

4

Differential effects of infliximab on absolute circulating blood leucocyte counts of innate immune cells in early and late rheumatoid arthritis patients.

Coulthard LR, Geiler J, Mathews RJ, Church LD, Dickie LJ, Cooper DL, Wong C, Savic S, Bryer D, Buch MH, Emery P, Morgan AW, McDermott MF. Coulthard LR, et al. Clin Exp Immunol. 2012 Oct;170(1):36-46. doi: 10.1111/j.1365-2249.2012.04626.x. Clin Exp Immunol. 2012. PMID: 22943199 Free PMC article. Clinical Trial.

5

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.

Mathews RJ, Robinson JI, Battellino M, Wong C, Taylor JC; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS); Eyre S, Churchman SM, Wilson AG, Isaacs JD, Hyrich K, Barton A, Plant D, Savic S, Cook GP, Sarzi-Puttini P, Emery P, Barrett JH, Morgan AW, McDermott MF. Mathews RJ, et al. Ann Rheum Dis. 2014 Jun;73(6):1202-10. doi: 10.1136/annrheumdis-2013-203276. Epub 2013 May 17. Ann Rheum Dis. 2014. PMID: 23687262

6

TLR dependent XBP-1 activation induces an autocrine loop in rheumatoid arthritis synoviocytes.

Savic S, Ouboussad L, Dickie LJ, Geiler J, Wong C, Doody GM, Churchman SM, Ponchel F, Emery P, Cook GP, Buch MH, Tooze RM, McDermott MF. Savic S, et al. J Autoimmun. 2014 May;50(100):59-66. doi: 10.1016/j.jaut.2013.11.002. Epub 2013 Dec 31. J Autoimmun. 2014. PMID: 24387801 Free PMC article.

7

Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations Results in Hyperresponsiveness to Lipopolysaccharide.

Harrison SR, Scambler T, Oubussad L, Wong C, Wittmann M, McDermott MF, Savic S. Harrison SR, et al. Front Immunol. 2018 Feb 6;9:173. doi: 10.3389/fimmu.2018.00173. eCollection 2018. Front Immunol. 2018. PMID: 29467762 Free PMC article.

8

Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation.

Lara-Reyna S, Scambler T, Holbrook J, Wong C, Jarosz-Griffiths HH, Martinon F, Savic S, Peckham D, McDermott MF. Lara-Reyna S, et al. Front Immunol. 2019 Aug 2;10:1789. doi: 10.3389/fimmu.2019.01789. eCollection 2019. Front Immunol. 2019. PMID: 31428093 Free PMC article.

9

ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis.

Scambler T, Jarosz-Griffiths HH, Lara-Reyna S, Pathak S, Wong C, Holbrook J, Martinon F, Savic S, Peckham D, McDermott MF. Scambler T, et al. Elife. 2019 Sep 18;8:e49248. doi: 10.7554/eLife.49248. Elife. 2019. PMID: 31532390 Free PMC article.

10

Revisiting p38 Mitogen-Activated Protein Kinases (MAPK) in Inflammatory Arthritis: A Narrative of the Emergence of MAPK-Activated Protein Kinase Inhibitors (MK2i).

Ganguly P, Macleod T, Wong C, Harland M, McGonagle D. Ganguly P, et al. Pharmaceuticals (Basel). 2023 Sep 12;16(9):1286. doi: 10.3390/ph16091286. Pharmaceuticals (Basel). 2023. PMID: 37765094 Free PMC article. Review.

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