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Hepatocyte regeneration is driven by embryo-like DNA methylation reprogramming.
Falick Michaeli T, Sabag O, Azria B, Fok R, Abudi N, Abramovitch R, Monin J, Gielchinsky Y, Cedar H, Bergman Y. Falick Michaeli T, et al. Among authors: abudi n. Proc Natl Acad Sci U S A. 2024 Apr 16;121(16):e2314885121. doi: 10.1073/pnas.2314885121. Epub 2024 Apr 8. Proc Natl Acad Sci U S A. 2024. PMID: 38588413 Free PMC article.
AN1284 attenuates steatosis, lipogenesis, and fibrosis in mice with pre-existing non-alcoholic steatohepatitis and directly affects aryl hydrocarbon receptor in a hepatic cell line.
Yehezkel AS, Abudi N, Nevo Y, Benyamini H, Elgavish S, Weinstock M, Abramovitch R. Yehezkel AS, et al. Among authors: abudi n. Front Endocrinol (Lausanne). 2023 Aug 16;14:1226808. doi: 10.3389/fendo.2023.1226808. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37664863 Free PMC article.