Hardingham GE - Search Results

1

Targeting mitochondrial dysfunction in amyotrophic lateral sclerosis: a systematic review and meta-analysis.

Mehta AR, Walters R, Waldron FM, Pal S, Selvaraj BT, Macleod MR, Hardingham GE, Chandran S, Gregory JM. Mehta AR, et al. Among authors: hardingham ge. Brain Commun. 2019 Aug 6;1(1):fcz009. doi: 10.1093/braincomms/fcz009. Brain Commun. 2019. PMID: 32133457 Free PMC article.

2

Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.

Patani R, Compston A, Puddifoot CA, Wyllie DJ, Hardingham GE, Allen ND, Chandran S. Patani R, et al. Among authors: hardingham ge. PLoS One. 2009 Oct 6;4(10):e7327. doi: 10.1371/journal.pone.0007327. PLoS One. 2009. PMID: 19806200 Free PMC article.

3

Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration.

Hardingham GE, Patani R, Baxter P, Wyllie DJ, Chandran S. Hardingham GE, et al. Mol Neurobiol. 2010 Aug;42(1):97-102. doi: 10.1007/s12035-010-8136-2. Epub 2010 Apr 30. Mol Neurobiol. 2010. PMID: 20431962 Free PMC article.

4

Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state.

Patani R, Hollins AJ, Wishart TM, Puddifoot CA, Alvarez S, de Lera AR, Wyllie DJ, Compston DA, Pedersen RA, Gillingwater TH, Hardingham GE, Allen ND, Chandran S. Patani R, et al. Among authors: hardingham ge. Nat Commun. 2011;2:214. doi: 10.1038/ncomms1216. Nat Commun. 2011. PMID: 21364553 Free PMC article.

5

Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms.

Gupta K, Patani R, Baxter P, Serio A, Story D, Tsujita T, Hayes JD, Pedersen RA, Hardingham GE, Chandran S. Gupta K, et al. Among authors: hardingham ge. Cell Death Differ. 2012 May;19(5):779-87. doi: 10.1038/cdd.2011.154. Epub 2011 Nov 18. Cell Death Differ. 2012. PMID: 22095276 Free PMC article.

6

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S. Bilican B, et al. Among authors: hardingham ge. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5803-8. doi: 10.1073/pnas.1202922109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451909 Free PMC article.

7

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis.

Patani R, Lewis PA, Trabzuni D, Puddifoot CA, Wyllie DJ, Walker R, Smith C, Hardingham GE, Weale M, Hardy J, Chandran S, Ryten M. Patani R, et al. Among authors: hardingham ge. J Neurochem. 2012 Aug;122(4):738-51. doi: 10.1111/j.1471-4159.2012.07825.x. Epub 2012 Jul 10. J Neurochem. 2012. PMID: 22681703 Free PMC article.

8

Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration.

Gupta K, Chandran S, Hardingham GE. Gupta K, et al. Among authors: hardingham ge. Br J Clin Pharmacol. 2013 Apr;75(4):907-18. doi: 10.1111/bcp.12022. Br J Clin Pharmacol. 2013. PMID: 23126226 Free PMC article. Review.

9

NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons.

Gupta K, Hardingham GE, Chandran S. Gupta K, et al. Among authors: hardingham ge. Neurosci Lett. 2013 May 24;543:95-100. doi: 10.1016/j.neulet.2013.03.010. Epub 2013 Mar 18. Neurosci Lett. 2013. PMID: 23518152 Free PMC article.

10

Physiological normoxia and absence of EGF is required for the long-term propagation of anterior neural precursors from human pluripotent cells.

Bilican B, Livesey MR, Haghi G, Qiu J, Burr K, Siller R, Hardingham GE, Wyllie DJ, Chandran S. Bilican B, et al. Among authors: hardingham ge. PLoS One. 2014 Jan 17;9(1):e85932. doi: 10.1371/journal.pone.0085932. eCollection 2014. PLoS One. 2014. PMID: 24465796 Free PMC article.

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