Gu L - Search Results

1

Glucagon receptor antagonist upregulates circulating GLP-1 level by promoting intestinal L-cell proliferation and GLP-1 production in type 2 diabetes.

Lang S, Yang J, Yang K, Gu L, Cui X, Wei T, Liu J, Le Y, Wang H, Wei R, Hong T. Lang S, et al. Among authors: gu l. BMJ Open Diabetes Res Care. 2020 Mar;8(1):e001025. doi: 10.1136/bmjdrc-2019-001025. BMJ Open Diabetes Res Care. 2020. PMID: 32139602 Free PMC article.

2

Liver-derived fibroblast growth factor 21 mediates effects of glucagon-like peptide-1 in attenuating hepatic glucose output.

Liu J, Yang K, Yang J, Xiao W, Le Y, Yu F, Gu L, Lang S, Tian Q, Jin T, Wei R, Hong T. Liu J, et al. Among authors: gu l. EBioMedicine. 2019 Mar;41:73-84. doi: 10.1016/j.ebiom.2019.02.037. Epub 2019 Mar 1. EBioMedicine. 2019. PMID: 30827929 Free PMC article. Clinical Trial.

3

Glucagon receptor antagonism increases mouse pancreatic δ-cell mass through cell proliferation and duct-derived neogenesis.

Gu L, Cui X, Lang S, Wang H, Hong T, Wei R. Gu L, et al. Biochem Biophys Res Commun. 2019 May 14;512(4):864-870. doi: 10.1016/j.bbrc.2019.03.148. Epub 2019 Mar 28. Biochem Biophys Res Commun. 2019. PMID: 30929915

4

Antagonistic Glucagon Receptor Antibody Promotes α-Cell Proliferation and Increases β-Cell Mass in Diabetic Mice.

Wei R, Gu L, Yang J, Yang K, Liu J, Le Y, Lang S, Wang H, Thai D, Yan H, Hong T. Wei R, et al. Among authors: gu l. iScience. 2019 Jun 28;16:326-339. doi: 10.1016/j.isci.2019.05.030. Epub 2019 May 30. iScience. 2019. PMID: 31203188 Free PMC article.

5

Liraglutide ameliorates palmitate-induced oxidative injury in islet microvascular endothelial cells through GLP-1 receptor/PKA and GTPCH1/eNOS signaling pathways.

Le Y, Wei R, Yang K, Lang S, Gu L, Liu J, Hong T, Yang J. Le Y, et al. Among authors: gu l. Peptides. 2020 Feb;124:170212. doi: 10.1016/j.peptides.2019.170212. Epub 2019 Nov 23. Peptides. 2020. PMID: 31770577

6

Glucagon receptor antagonism promotes the production of gut proglucagon-derived peptides in diabetic mice.

Lang S, Wei R, Wei T, Gu L, Feng J, Yan H, Yang J, Hong T. Lang S, et al. Among authors: gu l. Peptides. 2020 Sep;131:170349. doi: 10.1016/j.peptides.2020.170349. Epub 2020 Jun 16. Peptides. 2020. PMID: 32561493

7

Dapagliflozin promotes beta cell regeneration by inducing pancreatic endocrine cell phenotype conversion in type 2 diabetic mice.

Wei R, Cui X, Feng J, Gu L, Lang S, Wei T, Yang J, Liu J, Le Y, Wang H, Yang K, Hong T. Wei R, et al. Among authors: gu l. Metabolism. 2020 Oct;111:154324. doi: 10.1016/j.metabol.2020.154324. Epub 2020 Jul 23. Metabolism. 2020. PMID: 32712220 Free article.

8

Pro-α-cell-derived β-cells contribute to β-cell neogenesis induced by antagonistic glucagon receptor antibody in type 2 diabetic mice.

Cui X, Feng J, Wei T, Gu L, Wang D, Lang S, Yang K, Yang J, Yan H, Wei R, Hong T. Cui X, et al. Among authors: gu l. iScience. 2022 Jun 9;25(7):104567. doi: 10.1016/j.isci.2022.104567. eCollection 2022 Jul 15. iScience. 2022. PMID: 35789836 Free PMC article.

9

γ-aminobutyric acid modulates α-cell hyperplasia but not β-cell regeneration induced by glucagon receptor antagonism in type 1 diabetic mice.

Gu L, Cui X, Lin X, Yang J, Wei R, Hong T, Yang K. Gu L, et al. Acta Diabetol. 2023 Jan;60(1):19-28. doi: 10.1007/s00592-022-01970-4. Epub 2022 Sep 21. Acta Diabetol. 2023. PMID: 36129525

10

Glucagon Acting at the GLP-1 Receptor Contributes to β-Cell Regeneration Induced by Glucagon Receptor Antagonism in Diabetic Mice.

Wei T, Cui X, Jiang Y, Wang K, Wang D, Li F, Lin X, Gu L, Yang K, Yang J, Hong T, Wei R. Wei T, et al. Among authors: gu l. Diabetes. 2023 May 1;72(5):599-610. doi: 10.2337/db22-0784. Diabetes. 2023. PMID: 36826938 Free PMC article.

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