Klaholz BP - Search Results

1

Targeting the Human 80S Ribosome in Cancer: From Structure to Function and Drug Design for Innovative Adjuvant Therapeutic Strategies.

Gilles A, Frechin L, Natchiar K, Biondani G, Loeffelholz OV, Holvec S, Malaval JL, Winum JY, Klaholz BP, Peyron JF. Gilles A, et al. Among authors: klaholz bp. Cells. 2020 Mar 5;9(3):629. doi: 10.3390/cells9030629. Cells. 2020. PMID: 32151059 Free PMC article. Review.

2

Purification, characterization and crystallization of the human 80S ribosome.

Khatter H, Myasnikov AG, Mastio L, Billas IM, Birck C, Stella S, Klaholz BP. Khatter H, et al. Among authors: klaholz bp. Nucleic Acids Res. 2014 Apr;42(6):e49. doi: 10.1093/nar/gkt1404. Epub 2014 Jan 21. Nucleic Acids Res. 2014. PMID: 24452798 Free PMC article.

3

Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7.

Uchikawa E, Natchiar KS, Han X, Proux F, Roblin P, Zhang E, Durand A, Klaholz BP, Dock-Bregeon AC. Uchikawa E, et al. Among authors: klaholz bp. Nucleic Acids Res. 2015 Mar 31;43(6):3373-88. doi: 10.1093/nar/gkv173. Epub 2015 Mar 9. Nucleic Acids Res. 2015. PMID: 25753663 Free PMC article.

4

Structure of the human 80S ribosome.

Khatter H, Myasnikov AG, Natchiar SK, Klaholz BP. Khatter H, et al. Among authors: klaholz bp. Nature. 2015 Apr 30;520(7549):640-5. doi: 10.1038/nature14427. Epub 2015 Apr 22. Nature. 2015. PMID: 25901680

5

IBiSS, a versatile and interactive tool for integrated sequence and 3D structure analysis of large macromolecular complexes.

Beinsteiner B, Michalon J, Klaholz BP. Beinsteiner B, et al. Among authors: klaholz bp. Bioinformatics. 2015 Oct 15;31(20):3339-44. doi: 10.1093/bioinformatics/btv347. Epub 2015 Jun 19. Bioinformatics. 2015. PMID: 26092861

6

Structure-function insights reveal the human ribosome as a cancer target for antibiotics.

Myasnikov AG, Kundhavai Natchiar S, Nebout M, Hazemann I, Imbert V, Khatter H, Peyron JF, Klaholz BP. Myasnikov AG, et al. Among authors: klaholz bp. Nat Commun. 2016 Sep 26;7:12856. doi: 10.1038/ncomms12856. Nat Commun. 2016. PMID: 27665925 Free PMC article.

7

Focused classification and refinement in high-resolution cryo-EM structural analysis of ribosome complexes.

von Loeffelholz O, Natchiar SK, Djabeur N, Myasnikov AG, Kratzat H, Ménétret JF, Hazemann I, Klaholz BP. von Loeffelholz O, et al. Among authors: klaholz bp. Curr Opin Struct Biol. 2017 Oct;46:140-148. doi: 10.1016/j.sbi.2017.07.007. Epub 2017 Aug 29. Curr Opin Struct Biol. 2017. PMID: 28850874 Review.

8

Visualization of chemical modifications in the human 80S ribosome structure.

Natchiar SK, Myasnikov AG, Kratzat H, Hazemann I, Klaholz BP. Natchiar SK, et al. Among authors: klaholz bp. Nature. 2017 Nov 23;551(7681):472-477. doi: 10.1038/nature24482. Epub 2017 Nov 15. Nature. 2017. PMID: 29143818

9

Volta phase plate data collection facilitates image processing and cryo-EM structure determination.

von Loeffelholz O, Papai G, Danev R, Myasnikov AG, Natchiar SK, Hazemann I, Ménétret JF, Klaholz BP. von Loeffelholz O, et al. Among authors: klaholz bp. J Struct Biol. 2018 Jun;202(3):191-199. doi: 10.1016/j.jsb.2018.01.003. Epub 2018 Jan 11. J Struct Biol. 2018. PMID: 29337113

10

Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures.

Mortison JD, Schenone M, Myers JA, Zhang Z, Chen L, Ciarlo C, Comer E, Natchiar SK, Carr SA, Klaholz BP, Myers AG. Mortison JD, et al. Among authors: klaholz bp. Cell Chem Biol. 2018 Dec 20;25(12):1506-1518.e13. doi: 10.1016/j.chembiol.2018.09.010. Epub 2018 Oct 11. Cell Chem Biol. 2018. PMID: 30318461 Free PMC article.

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