Paine SW - Search Results

1

Hydrostatic pressure regulates CYP1A2 expression in human hepatocytes via a mechanosensitive aryl hydrocarbon receptor-dependent pathway.

Burton L, Scaife P, Paine SW, Mellor HR, Abernethy L, Littlewood P, Rauch C. Burton L, et al. Among authors: paine sw. Am J Physiol Cell Physiol. 2020 May 1;318(5):C889-C902. doi: 10.1152/ajpcell.00472.2019. Epub 2020 Mar 11. Am J Physiol Cell Physiol. 2020. PMID: 32159360 Free PMC article.

2

Can long range mechanical interaction between drugs and membrane proteins define the notion of molecular promiscuity? Application to P-glycoprotein-mediated multidrug resistance (MDR).

Rauch C, Paine SW, Littlewood P. Rauch C, et al. Among authors: paine sw. Biochim Biophys Acta. 2013 Nov;1830(11):5112-8. doi: 10.1016/j.bbagen.2013.06.038. Epub 2013 Jul 10. Biochim Biophys Acta. 2013. PMID: 23850561

3

A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions.

Cherkaoui-Rbati MH, Paine SW, Littlewood P, Rauch C. Cherkaoui-Rbati MH, et al. Among authors: paine sw. PLoS One. 2017 Sep 14;12(9):e0183794. doi: 10.1371/journal.pone.0183794. eCollection 2017. PLoS One. 2017. PMID: 28910306 Free PMC article.

4

The effects of aging on hepatic microsomal scaling factor and hepatocellularity number in the horse.

Shibany KA, Tötemeyer S, Pratt SL, Paine SW. Shibany KA, et al. Among authors: paine sw. Xenobiotica. 2018 Dec;48(12):1237-1244. doi: 10.1080/00498254.2017.1413263. Epub 2017 Dec 19. Xenobiotica. 2018. PMID: 29198170

5

Equine hepatocytes: isolation, cryopreservation, and applications to in vitro drug metabolism studies.

Shibany KA, Tötemeyer S, Pratt SL, Paine SW. Shibany KA, et al. Among authors: paine sw. Pharmacol Res Perspect. 2016 Sep 30;4(5):e00268. doi: 10.1002/prp2.268. eCollection 2016 Oct. Pharmacol Res Perspect. 2016. PMID: 27713829 Free PMC article.

6

Prediction of pharmacokinetic clearance and potential Drug-Drug interactions for omeprazole in the horse using in vitro systems.

Shibany KA, Pratt SL, Aldurdunji M, Totemeyer S, Paine SW. Shibany KA, et al. Among authors: paine sw. Xenobiotica. 2020 Oct;50(10):1220-1227. doi: 10.1080/00498254.2020.1764131. Epub 2020 May 20. Xenobiotica. 2020. PMID: 32369392

7

A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion.

White KL, Paine S, Harris J. White KL, et al. Vet Anaesth Analg. 2017 Jul;44(4):865-875. doi: 10.1016/j.vaa.2017.01.001. Epub 2017 Feb 1. Vet Anaesth Analg. 2017. PMID: 28318987

8

Re-evaluation of the regulation of omeprazole in racehorses: An evidence-based approach.

Viljanto M, Hillyer L, Hincks P, Pearce C, Paine SW. Viljanto M, et al. Among authors: paine sw. J Vet Pharmacol Ther. 2018 Jun;41(3):469-475. doi: 10.1111/jvp.12491. Epub 2018 Feb 22. J Vet Pharmacol Ther. 2018. PMID: 29468684

9

Plasma and urine pharmacokinetics of hydroxyzine and cetirizine following repeated oral administrations to exercised horses.

Paine SW, Aldurdunji M, Garth-Greeves A, Muir T, Hincks PR. Paine SW, et al. J Vet Pharmacol Ther. 2022 Jan;45(1):46-53. doi: 10.1111/jvp.13010. Epub 2021 Sep 1. J Vet Pharmacol Ther. 2022. PMID: 34469007

10

In silico human and rat Vss quantitative structure-activity relationship models.

Gleeson MP, Waters NJ, Paine SW, Davis AM. Gleeson MP, et al. Among authors: paine sw. J Med Chem. 2006 Mar 23;49(6):1953-63. doi: 10.1021/jm0510070. J Med Chem. 2006. PMID: 16539383

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