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The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques.
Webb GM, Molden J, Busman-Sahay K, Abdulhaqq S, Wu HL, Weber WC, Bateman KB, Reed JS, Northrup M, Maier N, Tanaka S, Gao L, Davey B, Carpenter BL, Axthelm MK, Stanton JJ, Smedley J, Greene JM, Safrit JT, Estes JD, Skinner PJ, Sacha JB. Webb GM, et al. Among authors: smedley j. PLoS Pathog. 2020 Mar 12;16(3):e1008339. doi: 10.1371/journal.ppat.1008339. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32163523 Free PMC article.
A macaque model of HIV-1 infection.
Hatziioannou T, Ambrose Z, Chung NP, Piatak M Jr, Yuan F, Trubey CM, Coalter V, Kiser R, Schneider D, Smedley J, Pung R, Gathuka M, Estes JD, Veazey RS, KewalRamani VN, Lifson JD, Bieniasz PD. Hatziioannou T, et al. Among authors: smedley j. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4425-9. doi: 10.1073/pnas.0812587106. Epub 2009 Mar 2. Proc Natl Acad Sci U S A. 2009. PMID: 19255423 Free PMC article.
Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection.
Minang JT, Trivett MT, Bolton DL, Trubey CM, Estes JD, Li Y, Smedley J, Pung R, Rosati M, Jalah R, Pavlakis GN, Felber BK, Piatak M Jr, Roederer M, Lifson JD, Ott DE, Ohlen C. Minang JT, et al. Among authors: smedley j. J Immunol. 2010 Jan 1;184(1):315-26. doi: 10.4049/jimmunol.0902410. Epub 2009 Nov 30. J Immunol. 2010. PMID: 19949091 Free PMC article.
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.
Estes JD, Harris LD, Klatt NR, Tabb B, Pittaluga S, Paiardini M, Barclay GR, Smedley J, Pung R, Oliveira KM, Hirsch VM, Silvestri G, Douek DC, Miller CJ, Haase AT, Lifson J, Brenchley JM. Estes JD, et al. Among authors: smedley j. PLoS Pathog. 2010 Aug 19;6(8):e1001052. doi: 10.1371/journal.ppat.1001052. PLoS Pathog. 2010. PMID: 20808901 Free PMC article.
Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.
Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW Jr, Nagashima K, Keele BF, Macallister R, Smedley J, Pathak VK, Kewalramani VN, Coffin JM, Lifson JD. Del Prete GQ, et al. Among authors: smedley j. J Virol. 2012 Mar;86(6):3152-66. doi: 10.1128/JVI.06886-11. Epub 2012 Jan 11. J Virol. 2012. PMID: 22238316 Free PMC article.
Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection.
Tabb B, Morcock DR, Trubey CM, Quiñones OA, Hao XP, Smedley J, Macallister R, Piatak M Jr, Harris LD, Paiardini M, Silvestri G, Brenchley JM, Alvord WG, Lifson JD, Estes JD. Tabb B, et al. Among authors: smedley j. J Infect Dis. 2013 Mar 15;207(6):880-92. doi: 10.1093/infdis/jis643. Epub 2012 Oct 19. J Infect Dis. 2013. PMID: 23087435 Free PMC article.
Molecularly tagged simian immunodeficiency virus SIVmac239 synthetic swarm for tracking independent infection events.
Del Prete GQ, Park H, Fennessey CM, Reid C, Lipkey L, Newman L, Oswald K, Kahl C, Piatak M Jr, Quiñones OA, Alvord WG, Smedley J, Estes JD, Lifson JD, Picker LJ, Keele BF. Del Prete GQ, et al. Among authors: smedley j. J Virol. 2014 Jul;88(14):8077-90. doi: 10.1128/JVI.01026-14. Epub 2014 May 7. J Virol. 2014. PMID: 24807714 Free PMC article.
HIV-1-induced AIDS in monkeys.
Hatziioannou T, Del Prete GQ, Keele BF, Estes JD, McNatt MW, Bitzegeio J, Raymond A, Rodriguez A, Schmidt F, Mac Trubey C, Smedley J, Piatak M Jr, KewalRamani VN, Lifson JD, Bieniasz PD. Hatziioannou T, et al. Among authors: smedley j. Science. 2014 Jun 20;344(6190):1401-5. doi: 10.1126/science.1250761. Science. 2014. PMID: 24948736 Free PMC article.
Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques.
Del Prete GQ, Shoemaker R, Oswald K, Lara A, Trubey CM, Fast R, Schneider DK, Kiser R, Coalter V, Wiles A, Wiles R, Freemire B, Keele BF, Estes JD, Quiñones OA, Smedley J, Macallister R, Sanchez RI, Wai JS, Tan CM, Alvord WG, Hazuda DJ, Piatak M Jr, Lifson JD. Del Prete GQ, et al. Among authors: smedley j. Antimicrob Agents Chemother. 2014 Nov;58(11):6790-806. doi: 10.1128/AAC.03746-14. Epub 2014 Sep 2. Antimicrob Agents Chemother. 2014. PMID: 25182644 Free PMC article.
173 results