Toyoshima J - Search Results

1

Model-based Prediction of the Long-term Glucose-Lowering Effects of Ipragliflozin, a Selective Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor, in Patients with Type 2 Diabetes Mellitus.

Saito M, Kaibara A, Kadokura T, Toyoshima J, Yoshida S, Kazuta K, Ueyama E. Saito M, et al. Among authors: toyoshima j. Diabetes Ther. 2020 Apr;11(4):951-964. doi: 10.1007/s13300-020-00785-2. Epub 2020 Mar 12. Diabetes Ther. 2020. PMID: 32166619 Free PMC article.

2

Pharmacokinetic drug interaction study between overactive bladder drugs mirabegron and tolterodine in Japanese healthy postmenopausal females.

Nomura Y, Iitsuka H, Toyoshima J, Kuroishi K, Hatta T, Kaibara A, Katashima M, Moy S, Sawamoto T. Nomura Y, et al. Among authors: toyoshima j. Drug Metab Pharmacokinet. 2016 Dec;31(6):411-416. doi: 10.1016/j.dmpk.2016.08.002. Epub 2016 Aug 18. Drug Metab Pharmacokinet. 2016. PMID: 27829538

3

Clinical pharmacology study of ipragliflozin in Japanese patients with type 1 diabetes mellitus: A phase 2, randomized, placebo-controlled trial.

Kaku K, Isaka H, Toyoshima J, Sakatani T. Kaku K, et al. Among authors: toyoshima j. Diabetes Obes Metab. 2019 Jun;21(6):1445-1454. doi: 10.1111/dom.13679. Epub 2019 Apr 8. Diabetes Obes Metab. 2019. PMID: 30821047 Free PMC article. Clinical Trial.

4

Pharmacokinetic and pharmacodynamic modelling for renal function dependent urinary glucose excretion effect of ipragliflozin, a selective sodium-glucose cotransporter 2 inhibitor, both in healthy subjects and patients with type 2 diabetes mellitus.

Saito M, Kaibara A, Kadokura T, Toyoshima J, Yoshida S, Kazuta K, Ueyama E. Saito M, et al. Among authors: toyoshima j. Br J Clin Pharmacol. 2019 Aug;85(8):1808-1819. doi: 10.1111/bcp.13972. Epub 2019 Jun 20. Br J Clin Pharmacol. 2019. PMID: 31026084 Free PMC article. Clinical Trial.

5

Efficacy and safety of ipragliflozin add-on therapy to insulin in Japanese patients with type 1 diabetes mellitus: A randomized, double-blind, phase 3 trial.

Kaku K, Isaka H, Sakatani T, Toyoshima J. Kaku K, et al. Among authors: toyoshima j. Diabetes Obes Metab. 2019 Oct;21(10):2284-2293. doi: 10.1111/dom.13807. Epub 2019 Jul 11. Diabetes Obes Metab. 2019. PMID: 31173455 Free PMC article. Clinical Trial.

6

Long-term (52-week) efficacy and safety of ipragliflozin add-on therapy to insulin in Japanese patients with type 1 diabetes mellitus: An uncontrolled, open-label extension of a phase III study.

Kaku K, Isaka H, Sakatani T, Toyoshima J. Kaku K, et al. Among authors: toyoshima j. J Diabetes Investig. 2020 May;11(3):662-671. doi: 10.1111/jdi.13181. Epub 2020 Feb 20. J Diabetes Investig. 2020. PMID: 31743569 Free PMC article. Clinical Trial.

7

Pharmacokinetics, Pharmacodynamics, and Safety of Peficitinib (ASP015K) in Healthy Male Caucasian and Japanese Subjects.

Shibata M, Hatta T, Saito M, Toyoshima J, Kaneko Y, Oda K, Nishimura T. Shibata M, et al. Among authors: toyoshima j. Clin Drug Investig. 2020 May;40(5):469-484. doi: 10.1007/s40261-020-00910-w. Clin Drug Investig. 2020. PMID: 32274653 Free PMC article. Clinical Trial.

8

Comparison of the Pharmacokinetic and Pharmacodynamic Relationship of Ipragliflozin Between Patients With Type 1 and Type 2 Diabetes Mellitus.

Toyoshima J, Saito M, Kaibara A, Isaka H, Sakatani T. Toyoshima J, et al. Clin Ther. 2020 Sep;42(9):1787-1798.e3. doi: 10.1016/j.clinthera.2020.07.009. Epub 2020 Aug 21. Clin Ther. 2020. PMID: 32839028 Clinical Trial.

9

Population pharmacokinetic analysis of peficitinib in patients with rheumatoid arthritis.

Toyoshima J, Shibata M, Kaibara A, Kaneko Y, Izutsu H, Nishimura T. Toyoshima J, et al. Br J Clin Pharmacol. 2021 Apr;87(4):2014-2022. doi: 10.1111/bcp.14605. Epub 2020 Dec 1. Br J Clin Pharmacol. 2021. PMID: 33068028 Free PMC article.

10

Exposure-response modeling of peficitinib efficacy in patients with rheumatoid arthritis.

Toyoshima J, Kaibara A, Shibata M, Kaneko Y, Izutsu H, Nishimura T. Toyoshima J, et al. Pharmacol Res Perspect. 2021 May;9(3):e00744. doi: 10.1002/prp2.744. Pharmacol Res Perspect. 2021. PMID: 33929089 Free PMC article.

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