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Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis.
Ding J, Ning B, Gong W, Wen W, Wu K, Liang J, He G, Huang S, Sun W, Han T, Huang L, Cao G, Wu M, Xie W, Wang H. Ding J, et al. Among authors: sun w. J Biol Chem. 2009 Nov 27;284(48):33311-9. doi: 10.1074/jbc.M109.046417. Epub 2009 Sep 29. J Biol Chem. 2009. PMID: 19801633 Free PMC article.
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