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Page 1
Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto-Kakizaki rats improves glucose homeostasis through enhanced FXR signalling.
Péan N, Le Lay A, Brial F, Wasserscheid J, Rouch C, Vincent M, Myridakis A, Hedjazi L, Dumas ME, Grundberg E, Lathrop M, Magnan C, Dewar K, Gauguier D. Péan N, et al. Diabetologia. 2020 Jun;63(6):1223-1235. doi: 10.1007/s00125-020-05122-7. Epub 2020 Mar 16. Diabetologia. 2020. PMID: 32173762 Free PMC article.
The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function.
Brial F, Alzaid F, Sonomura K, Kamatani Y, Meneyrol K, Le Lay A, Péan N, Hedjazi L, Sato TA, Venteclef N, Magnan C, Lathrop M, Dumas ME, Matsuda F, Zalloua P, Gauguier D. Brial F, et al. Among authors: pean n. Cell Rep. 2020 Feb 18;30(7):2306-2320.e5. doi: 10.1016/j.celrep.2020.01.066. Cell Rep. 2020. PMID: 32075738 Free article.
Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance.
Dumas ME, Rothwell AR, Hoyles L, Aranias T, Chilloux J, Calderari S, Noll EM, Péan N, Boulangé CL, Blancher C, Barton RH, Gu Q, Fearnside JF, Deshayes C, Hue C, Scott J, Nicholson JK, Gauguier D. Dumas ME, et al. Among authors: pean n. Cell Rep. 2017 Jul 5;20(1):136-148. doi: 10.1016/j.celrep.2017.06.039. Cell Rep. 2017. PMID: 28683308 Free PMC article.
The Bile Acid Receptor TGR5 and Liver Regeneration.
Jourdainne V, Péan N, Doignon I, Humbert L, Rainteau D, Tordjmann T. Jourdainne V, et al. Among authors: pean n. Dig Dis. 2015;33(3):319-26. doi: 10.1159/000371668. Epub 2015 May 27. Dig Dis. 2015. PMID: 26045264
TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function.
Merlen G, Kahale N, Ursic-Bedoya J, Bidault-Jourdainne V, Simerabet H, Doignon I, Tanfin Z, Garcin I, Péan N, Gautherot J, Davit-Spraul A, Guettier C, Humbert L, Rainteau D, Ebnet K, Ullmer C, Cassio D, Tordjmann T. Merlen G, et al. Among authors: pean n. Gut. 2020 Jan;69(1):146-157. doi: 10.1136/gutjnl-2018-316975. Epub 2019 Feb 5. Gut. 2020. PMID: 30723104
TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload.
Bidault-Jourdainne V, Merlen G, Glénisson M, Doignon I, Garcin I, Péan N, Boisgard R, Ursic-Bedoya J, Serino M, Ullmer C, Humbert L, Abdelrafee A, Golse N, Vibert E, Duclos-Vallée JC, Rainteau D, Tordjmann T. Bidault-Jourdainne V, et al. Among authors: pean n. JHEP Rep. 2020 Nov 11;3(2):100214. doi: 10.1016/j.jhepr.2020.100214. eCollection 2021 Apr. JHEP Rep. 2020. PMID: 33604531 Free PMC article.
Gut microbiota and bile acids: an old story revisited (again).
Péan N, Doignon I, Tordjmann T. Péan N, et al. Clin Res Hepatol Gastroenterol. 2014 Apr;38(2):129-31. doi: 10.1016/j.clinre.2013.06.006. Epub 2013 Jul 31. Clin Res Hepatol Gastroenterol. 2014. PMID: 23916556 No abstract available.