Stefanes NM - Search Results

1

Aldehyde biphenyl chalcones induce immunogenic apoptotic-like cell death and are promising new safe compounds against a wide range of hematologic cancers.

Maioral MF, Stefanes NM, Neuenfeldt PD, Chiaradia-Delatorre LD, Nunes RJ, Santos-Silva MC. Maioral MF, et al. Among authors: stefanes nm. Future Med Chem. 2020 Apr;12(8):673-688. doi: 10.4155/fmc-2019-0228. Epub 2020 Mar 19. Future Med Chem. 2020. PMID: 32191531

2

Cytotoxic effect of a novel naphthylchalcone against multiple cancer cells focusing on hematologic malignancies.

Maioral MF, Bodack CDN, Stefanes NM, Bigolin Á, Mascarello A, Chiaradia-Delatorre LD, Yunes RA, Nunes RJ, Santos-Silva MC. Maioral MF, et al. Among authors: stefanes nm. Biochimie. 2017 Sep;140:48-57. doi: 10.1016/j.biochi.2017.06.004. Epub 2017 Jun 10. Biochimie. 2017. PMID: 28610775 Free article.

3

Synthesis of novel pyrazoline derivatives and the evaluation of death mechanisms involved in their antileukemic activity.

Stefanes NM, Toigo J, Maioral MF, Jacques AV, Chiaradia-Delatorre LD, Perondi DM, Ribeiro AAB, Bigolin Á, Pirath IMS, Duarte BF, Nunes RJ, Santos-Silva MC. Stefanes NM, et al. Bioorg Med Chem. 2019 Jan 15;27(2):375-382. doi: 10.1016/j.bmc.2018.12.012. Epub 2018 Dec 7. Bioorg Med Chem. 2019. PMID: 30579801

4

Synthesis of chalcones derived from 1-naphthylacetophenone and evaluation of their cytotoxic and apoptotic effects in acute leukemia cell lines.

Jacques AV, Stefanes NM, Walter LO, Perondi DM, Efe FDL, de Souza LFS, Sens L, Syracuse SM, de Moraes ACR, de Oliveira AS, Martins CT, Magalhaes LG, Andricopulo AD, Silva LO, Nunes RJ, Santos-Silva MC. Jacques AV, et al. Among authors: stefanes nm. Bioorg Chem. 2021 Nov;116:105315. doi: 10.1016/j.bioorg.2021.105315. Epub 2021 Sep 1. Bioorg Chem. 2021. PMID: 34496319

5

A novel thiosemicarbazone as a promising effective and selective compound for acute leukemia.

Perondi DM, Jacques AV, Stefanes NM, Maioral MF, Sens L, Pacheco LA, Cury NM, Nunes RJ, Yunes JA, Santos-Silva MC. Perondi DM, et al. Among authors: stefanes nm. Anticancer Drugs. 2019 Sep;30(8):828-837. doi: 10.1097/CAD.0000000000000780. Anticancer Drugs. 2019. PMID: 30932944

6

Cytotoxic mechanisms of primin, a natural quinone isolated from Eugenia hiemalis, on hematological cancer cell lines.

Bigolin A, Maioral MF, Stefanes NM, Zatelli GA, Philippus AC, Falkenberg MB, Santos-Silva MC. Bigolin A, et al. Among authors: stefanes nm. Anticancer Drugs. 2020 Aug;31(7):709-717. doi: 10.1097/CAD.0000000000000937. Anticancer Drugs. 2020. PMID: 32639281

7

MICONIDINE acetate, a new selective and cytotoxic compound with synergic potential, induces cell cycle arrest and apoptosis in leukemia cells.

Maioral MF, Stefanes NM, Bigolin Á, Zatelli GA, Philippus AC, de Barcellos Falkenberg M, Santos-Silva MC. Maioral MF, et al. Among authors: stefanes nm. Invest New Drugs. 2019 Oct;37(5):912-922. doi: 10.1007/s10637-018-0694-6. Epub 2018 Dec 19. Invest New Drugs. 2019. PMID: 30569243

8

A new and efficient carboxymethyl-hexanoyl chitosan/dodecyl sulfate nanocarrier for a pyrazoline with antileukemic activity.

Chamorro Rengifo AF, Stefanes N, Toigo J, Mendes C, Santos-Silva MC, Nunes RJ, Parize AL, Minatti E. Chamorro Rengifo AF, et al. Mater Sci Eng C Mater Biol Appl. 2019 Dec;105:110051. doi: 10.1016/j.msec.2019.110051. Epub 2019 Aug 19. Mater Sci Eng C Mater Biol Appl. 2019. PMID: 31546341

9

A novel naphthylchalcone ([E]-4-(3-[naphthalen-2-yl]-3-oxoprop-1-en-1-yl) induces intrinsic and extrinsic apoptosis in human acute leukemia cell lines.

Jacques AV, Stefanes NM, Walter LO, Syracuse SM, Bigolin A, Chiaradia-Delatorre LD, de Souza LFS, de Moraes ACR, Nunes RJ, Santos-Silva MC. Jacques AV, et al. Among authors: stefanes nm. Fundam Clin Pharmacol. 2025 Feb;39(1):e13047. doi: 10.1111/fcp.13047. Fundam Clin Pharmacol. 2025. PMID: 39749431

10

Sodium diethyldithiocarbamate trihydrate: an effective and selective compound for hematological malignancies.

Stefanes NM, de Oliveira Silva L, Walter LO, Steimbach JV, Markendorf E, Ribeiro AAB, Feuser PE, Cordeiro AP, Santos-Silva MC. Stefanes NM, et al. Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug 26. doi: 10.1007/s00210-024-03399-8. Online ahead of print. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 39186189

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