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Structural basis of Gs and Gi recognition by the human glucagon receptor.
Qiao A, Han S, Li X, Li Z, Zhao P, Dai A, Chang R, Tai L, Tan Q, Chu X, Ma L, Thorsen TS, Reedtz-Runge S, Yang D, Wang MW, Sexton PM, Wootten D, Sun F, Zhao Q, Wu B. Qiao A, et al. Among authors: chang r. Science. 2020 Mar 20;367(6484):1346-1352. doi: 10.1126/science.aaz5346. Science. 2020. PMID: 32193322
Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors.
Zhao F, Zhou Q, Cong Z, Hang K, Zou X, Zhang C, Chen Y, Dai A, Liang A, Ming Q, Wang M, Chen LN, Xu P, Chang R, Feng W, Xia T, Zhang Y, Wu B, Yang D, Zhao L, Xu HE, Wang MW. Zhao F, et al. Among authors: chang r. Nat Commun. 2022 Feb 25;13(1):1057. doi: 10.1038/s41467-022-28683-0. Nat Commun. 2022. PMID: 35217653 Free PMC article.
Drug Development.
Chang RT, Chandrashekar DV, Roules GC, Iwasaki E, Jagadeesan N, Sumbria RK. Chang RT, et al. Alzheimers Dement. 2024 Dec;20 Suppl 6(Suppl 6):e090625. doi: 10.1002/alz.090625. Alzheimers Dement. 2024. PMID: 39782653 Free PMC article.
4,116 results