Zaino AM - Search Results

1

Probing the Protein-Protein Interaction Between the ATRX_ADD Domain and the Histone H3 Tail.

Zaino AM, Dash RC, Hadden MK. Zaino AM, et al. Molecules. 2020 Mar 25;25(7):1500. doi: 10.3390/molecules25071500. Molecules. 2020. PMID: 32218364 Free PMC article.

2

A metadynamic approach to understand the recognition mechanism of the histone H3 tail with the ATRX_ADD domain.

Dash RC, Zaino AM, Hadden MK. Dash RC, et al. Among authors: zaino am. Biochim Biophys Acta Gene Regul Mech. 2018 Jun;1861(6):594-602. doi: 10.1016/j.bbagrm.2018.05.001. Epub 2018 May 3. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 29730439

3

Structure-Activity Relationships for Itraconazole-Based Triazolone Analogues as Hedgehog Pathway Inhibitors.

Pace JR, Teske KA, Chau LQ, Dash RC, Zaino AM, Wechsler-Reya RJ, Hadden MK. Pace JR, et al. Among authors: zaino am. J Med Chem. 2019 Apr 25;62(8):3873-3885. doi: 10.1021/acs.jmedchem.8b01283. Epub 2019 Apr 5. J Med Chem. 2019. PMID: 30896941 Free PMC article.

4

HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis.

Bai G, Kermi C, Stoy H, Schiltz CJ, Bacal J, Zaino AM, Hadden MK, Eichman BF, Lopes M, Cimprich KA. Bai G, et al. Among authors: zaino am. Mol Cell. 2020 Jun 18;78(6):1237-1251.e7. doi: 10.1016/j.molcel.2020.04.031. Epub 2020 May 21. Mol Cell. 2020. PMID: 32442397 Free PMC article.

5

Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability.

Nayak S, Calvo JA, Cong K, Peng M, Berthiaume E, Jackson J, Zaino AM, Vindigni A, Hadden MK, Cantor SB. Nayak S, et al. Among authors: zaino am. Sci Adv. 2020 Jun 10;6(24):eaaz7808. doi: 10.1126/sciadv.aaz7808. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32577513 Free PMC article.

6

Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.

McPherson KS, Zaino AM, Dash RC, Rizzo AA, Li Y, Hao B, Bezsonova I, Hadden MK, Korzhnev DM. McPherson KS, et al. Among authors: zaino am. ChemMedChem. 2021 Apr 8;16(7):1126-1132. doi: 10.1002/cmdc.202000893. Epub 2021 Jan 28. ChemMedChem. 2021. PMID: 33314657 Free PMC article.

7

Structure-based virtual screening identifies an 8-hydroxyquinoline as a small molecule GLI1 inhibitor.

Dash RC, Wen J, Zaino AM, Morel SR, Chau LQ, Wechsler-Reya RJ, Hadden MK. Dash RC, et al. Among authors: zaino am. Mol Ther Oncolytics. 2021 Jan 16;20:265-276. doi: 10.1016/j.omto.2021.01.004. eCollection 2021 Mar 26. Mol Ther Oncolytics. 2021. PMID: 33614910 Free PMC article.

8

Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction.

Zaino AM, Dash RC, James SJ, MacGilvary N, Crompton A, McPherson KS, Stanzione M, Korzhnev DM, Dyson NJ, Chatterjee N, Cantor SB, Hadden MK. Zaino AM, et al. Bioorg Med Chem. 2024 May 15;106:117755. doi: 10.1016/j.bmc.2024.117755. Epub 2024 May 9. Bioorg Med Chem. 2024. PMID: 38749343

9

8-Hydroxyquinoline derivatives suppress GLI1-mediated transcription through multiple mechanisms.

Wen J, Charan Dash R, Zaino AM, Harrahill NJ, Calhoun JT, Dusek CO, Morel SR, Russolillo M, Kyle Hadden M. Wen J, et al. Among authors: zaino am. Bioorg Chem. 2023 Mar;132:106387. doi: 10.1016/j.bioorg.2023.106387. Epub 2023 Jan 21. Bioorg Chem. 2023. PMID: 36724660

10

Exploring the physicochemical and antiproliferative properties of biaryl-linked [13]-macrodilactones.

Chen C, Bosko C, McGeough CP, McLean R, Zaino AM, Kyle Hadden M, Peczuh MW. Chen C, et al. Among authors: zaino am. Bioorg Med Chem. 2020 Oct 15;28(20):115671. doi: 10.1016/j.bmc.2020.115671. Epub 2020 Aug 8. Bioorg Med Chem. 2020. PMID: 33069068

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