Oberley-Deegan RE - Search Results

1

Manganese porphyrin, MnTE-2-PyP, treatment protects the prostate from radiation-induced fibrosis (RIF) by activating the NRF2 signaling pathway and enhancing SOD2 and sirtuin activity.

Shrishrimal S, Chatterjee A, Kosmacek EA, Davis PJ, McDonald JT, Oberley-Deegan RE. Shrishrimal S, et al. Free Radic Biol Med. 2020 May 20;152:255-270. doi: 10.1016/j.freeradbiomed.2020.03.014. Epub 2020 Mar 25. Free Radic Biol Med. 2020. PMID: 32222469 Free PMC article.

2

MnTE-2-PyP reduces prostate cancer growth and metastasis by suppressing p300 activity and p300/HIF-1/CREB binding to the promoter region of the PAI-1 gene.

Tong Q, Weaver MR, Kosmacek EA, O'Connor BP, Harmacek L, Venkataraman S, Oberley-Deegan RE. Tong Q, et al. Free Radic Biol Med. 2016 May;94:185-94. doi: 10.1016/j.freeradbiomed.2016.02.036. Epub 2016 Mar 2. Free Radic Biol Med. 2016. PMID: 26944191 Free PMC article.

3

MnTE-2-PyP modulates thiol oxidation in a hydrogen peroxide-mediated manner in a human prostate cancer cell.

Tong Q, Zhu Y, Galaske JW, Kosmacek EA, Chatterjee A, Dickinson BC, Oberley-Deegan RE. Tong Q, et al. Free Radic Biol Med. 2016 Dec;101:32-43. doi: 10.1016/j.freeradbiomed.2016.09.019. Epub 2016 Sep 24. Free Radic Biol Med. 2016. PMID: 27671770 Free PMC article.

4

MnTE-2-PyP Treatment, or NOX4 Inhibition, Protects against Radiation-Induced Damage in Mouse Primary Prostate Fibroblasts by Inhibiting the TGF-Beta 1 Signaling Pathway.

Chatterjee A, Kosmacek EA, Oberley-Deegan RE. Chatterjee A, et al. Radiat Res. 2017 Mar;187(3):367-381. doi: 10.1667/RR14623.1. Epub 2017 Feb 22. Radiat Res. 2017. PMID: 28225655 Free PMC article.

5

The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues.

Shrishrimal S, Kosmacek EA, Chatterjee A, Tyson MJ, Oberley-Deegan RE. Shrishrimal S, et al. Antioxidants (Basel). 2017 Nov 6;6(4):87. doi: 10.3390/antiox6040087. Antioxidants (Basel). 2017. PMID: 29113120 Free PMC article.

6

Reactive Oxygen Species Drive Epigenetic Changes in Radiation-Induced Fibrosis.

Shrishrimal S, Kosmacek EA, Oberley-Deegan RE. Shrishrimal S, et al. Oxid Med Cell Longev. 2019 Feb 6;2019:4278658. doi: 10.1155/2019/4278658. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 30881591 Free PMC article. Review.

7

p66Shc protein through a redox mechanism enhances the progression of prostate cancer cells towards castration-resistance.

Miller DR, Ingersoll MA, Chatterjee A, Baker B, Shrishrimal S, Kosmacek EA, Zhu Y, Cheng PW, Oberley-Deegan RE, Lin MF. Miller DR, et al. Free Radic Biol Med. 2019 Aug 1;139:24-34. doi: 10.1016/j.freeradbiomed.2019.05.015. Epub 2019 May 14. Free Radic Biol Med. 2019. PMID: 31100478 Free PMC article.

8

MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses.

Chatterjee A, Kosmacek EA, Shrishrimal S, McDonald JT, Oberley-Deegan RE. Chatterjee A, et al. Redox Biol. 2020 Jul;34:101542. doi: 10.1016/j.redox.2020.101542. Epub 2020 Apr 21. Redox Biol. 2020. PMID: 32361681 Free PMC article.

9

MnTE-2-PyP Suppresses Prostate Cancer Cell Growth via H₂O₂ Production.

Zhu Y, Kosmacek EA, Chatterjee A, Oberley-Deegan RE. Zhu Y, et al. Antioxidants (Basel). 2020 Jun 4;9(6):490. doi: 10.3390/antiox9060490. Antioxidants (Basel). 2020. PMID: 32512786 Free PMC article.

10

MnTE-2-PyP protects fibroblast mitochondria from hyperglycemia and radiation exposure.

Chatterjee A, Sakallioglu IT, Murthy D, Kosmacek EA, Singh PK, McDonald JT, Powers R, Oberley-Deegan RE. Chatterjee A, et al. Among authors: oberley deegan re. Redox Biol. 2022 Jun;52:102301. doi: 10.1016/j.redox.2022.102301. Epub 2022 Mar 24. Redox Biol. 2022. PMID: 35358851 Free PMC article.

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