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Page 1
Meprin β cleaves TREM2 and controls its phagocytic activity on macrophages.
Berner DK, Wessolowski L, Armbrust F, Schneppenheim J, Schlepckow K, Koudelka T, Scharfenberg F, Lucius R, Tholey A, Kleinberger G, Haass C, Arnold P, Becker-Pauly C. Berner DK, et al. Among authors: armbrust f. FASEB J. 2020 May;34(5):6675-6687. doi: 10.1096/fj.201902183R. Epub 2020 Apr 1. FASEB J. 2020. PMID: 32237095
Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes.
Peters F, Scharfenberg F, Colmorgen C, Armbrust F, Wichert R, Arnold P, Potempa B, Potempa J, Pietrzik CU, Häsler R, Rosenstiel P, Becker-Pauly C. Peters F, et al. Among authors: armbrust f. FASEB J. 2019 Jun;33(6):7490-7504. doi: 10.1096/fj.201802391R. Epub 2019 Mar 27. FASEB J. 2019. PMID: 30916990 Free PMC article.
Comparison of the transcriptional gene analysis data with gene analyses of IBD patients revealed that different gene subsets were dysregulated if meprin alpha was expressed alone or in the enzyme complex, demonstrating the physiologic and pathophysiological relevance of the mepri …
Comparison of the transcriptional gene analysis data with gene analyses of IBD patients revealed that different gene subsets were dysregulat …
Characterization of the Cancer-Associated Meprin Βeta Variants G45R and G89R.
Gellrich A, Scharfenberg F, Peters F, Sammel M, Helm O, Armbrust F, Schmidt F, Lokau J, Garbers C, Sebens S, Arnold P, Becker-Pauly C. Gellrich A, et al. Among authors: armbrust f. Front Mol Biosci. 2021 Oct 6;8:702341. doi: 10.3389/fmolb.2021.702341. eCollection 2021. Front Mol Biosci. 2021. PMID: 34692768 Free PMC article.
Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease.
Marengo L, Armbrust F, Schoenherr C, Storck SE, Schmitt U, Zampar S, Wirths O, Altmeppen H, Glatzel M, Kaether C, Weggen S, Becker-Pauly C, Pietrzik CU. Marengo L, et al. Among authors: armbrust f. Cell Mol Life Sci. 2022 Mar 2;79(3):168. doi: 10.1007/s00018-022-04205-5. Cell Mol Life Sci. 2022. PMID: 35235058 Free PMC article.
MT1-MMP and ADAM10/17 exhibit a remarkable overlap of shedding properties.
Werny L, Grogro A, Bickenbach K, Bülck C, Armbrust F, Koudelka T, Pathak K, Scharfenberg F, Sammel M, Sheikhouny F, Tholey A, Linder S, Becker-Pauly C. Werny L, et al. Among authors: armbrust f. FEBS J. 2023 Jan;290(1):93-111. doi: 10.1111/febs.16586. Epub 2022 Aug 9. FEBS J. 2023. PMID: 35944080 Free article.
Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis.
Bülck C, Nyström EEL, Koudelka T, Mannbar-Frahm M, Andresen G, Radhouani M, Tran F, Scharfenberg F, Schrell F, Armbrust F, Dahlke E, Zhao B, Vervaeke A, Theilig F, Rosenstiel P, Starkl P, Rosshart SP, Fickenscher H, Tholey A, Hansson GC, Becker-Pauly C. Bülck C, et al. Among authors: armbrust f. Sci Adv. 2023 Mar 31;9(13):eadf4055. doi: 10.1126/sciadv.adf4055. Epub 2023 Mar 31. Sci Adv. 2023. PMID: 37000885 Free PMC article.
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