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Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways.
Bajaj A, Ihegword A, Qiu C, Small AM, Wei WQ, Bastarache L, Feng Q, Kember RL, Risman M, Bloom RD, Birtwell DL, Williams H, Shaffer CM, Chen J, Center RG, Denny JC, Rader DJ, Stein CM, Damrauer SM, Susztak K. Bajaj A, et al. Among authors: kember rl. Kidney Int. 2020 May;97(5):1032-1041. doi: 10.1016/j.kint.2020.01.027. Epub 2020 Feb 17. Kidney Int. 2020. PMID: 32247630 Free PMC article.
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits.
Hartwell EE, Jinwala Z, Milone J, Ramirez S, Gelernter J, Kranzler HR, Kember RL. Hartwell EE, et al. Among authors: kember rl. medRxiv [Preprint]. 2024 Jan 23:2024.01.22.24301615. doi: 10.1101/2024.01.22.24301615. medRxiv. 2024. Update in: Neuropsychopharmacology. 2024 Dec;49(13):1958-1967. doi: 10.1038/s41386-024-01922-2 PMID: 38343859 Free PMC article. Updated. Preprint.
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens.
Reiner BC, Chehimi SN, Merkel R, Toikumo S, Berrettini WH, Kranzler HR, Sanchez-Roige S, Kember RL, Schmidt HD, Crist RC. Reiner BC, et al. Among authors: kember rl. bioRxiv [Preprint]. 2024 May 26:2024.05.26.595949. doi: 10.1101/2024.05.26.595949. bioRxiv. 2024. Update in: Sci Rep. 2024 Aug 6;14(1):18258. doi: 10.1038/s41598-024-69255-0 PMID: 38826289 Free PMC article. Updated. Preprint.
Genomic Risk Stratification Predicts All-Cause Mortality After Cardiac Catheterization.
Levin MG, Kember RL, Judy R, Birtwell D, Williams H, Arany Z, Giri J, Guerraty M, Cappola T; Regeneron Genetics Center; Chen J, Rader DJ, Damrauer SM. Levin MG, et al. Among authors: kember rl. Circ Genom Precis Med. 2018 Nov;11(11):e002352. doi: 10.1161/CIRCGEN.118.002352. Circ Genom Precis Med. 2018. PMID: 30571185 Free PMC article.
Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors.
AlDubayan SH, Pyle LC, Gamulin M, Kulis T, Moore ND, Taylor-Weiner A, Hamid AA, Reardon B, Wubbenhorst B, Godse R, Vaughn DJ, Jacobs LA, Meien S, Grgic M, Kastelan Z, Markt SC, Damrauer SM, Rader DJ, Kember RL, Loud JT, Kanetsky PA, Greene MH, Sweeney CJ, Kubisch C, Nathanson KL, Van Allen EM, Stewart DR, Lessel D; Regeneron Genetics Center (RGC) Research Team. AlDubayan SH, et al. Among authors: kember rl. JAMA Oncol. 2019 Apr 1;5(4):514-522. doi: 10.1001/jamaoncol.2018.6477. JAMA Oncol. 2019. PMID: 30676620 Free PMC article.
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
Kranzler HR, Zhou H, Kember RL, Vickers Smith R, Justice AC, Damrauer S, Tsao PS, Klarin D, Baras A, Reid J, Overton J, Rader DJ, Cheng Z, Tate JP, Becker WC, Concato J, Xu K, Polimanti R, Zhao H, Gelernter J. Kranzler HR, et al. Among authors: kember rl. Nat Commun. 2019 Apr 2;10(1):1499. doi: 10.1038/s41467-019-09480-8. Nat Commun. 2019. PMID: 30940813 Free PMC article.
Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
Kranzler HR, Zhou H, Kember RL, Smith RV, Justice AC, Damrauer S, Tsao PS, Klarin D, Baras A, Reid J, Overton J, Rader DJ, Cheng Z, Tate JP, Becker WC, Concato J, Xu K, Polimanti R, Zhao H, Gelernter J. Kranzler HR, et al. Among authors: kember rl. Nat Commun. 2019 May 17;10(1):2275. doi: 10.1038/s41467-019-10254-5. Nat Commun. 2019. PMID: 31101824 Free PMC article.
115 results