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Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer.
Fell JB, Fischer JP, Baer BR, Blake JF, Bouhana K, Briere DM, Brown KD, Burgess LE, Burns AC, Burkard MR, Chiang H, Chicarelli MJ, Cook AW, Gaudino JJ, Hallin J, Hanson L, Hartley DP, Hicken EJ, Hingorani GP, Hinklin RJ, Mejia MJ, Olson P, Otten JN, Rhodes SP, Rodriguez ME, Savechenkov P, Smith DJ, Sudhakar N, Sullivan FX, Tang TP, Vigers GP, Wollenberg L, Christensen JG, Marx MA. Fell JB, et al. Among authors: hanson l. J Med Chem. 2020 Jul 9;63(13):6679-6693. doi: 10.1021/acs.jmedchem.9b02052. Epub 2020 Apr 6. J Med Chem. 2020. PMID: 32250617 Free article.
Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo Activity.
Fell JB, Fischer JP, Baer BR, Ballard J, Blake JF, Bouhana K, Brandhuber BJ, Briere DM, Burgess LE, Burkard MR, Chiang H, Chicarelli MJ, Davidson K, Gaudino JJ, Hallin J, Hanson L, Hee K, Hicken EJ, Hinklin RJ, Marx MA, Mejia MJ, Olson P, Savechenkov P, Sudhakar N, Tang TP, Vigers GP, Zecca H, Christensen JG. Fell JB, et al. Among authors: hanson l. ACS Med Chem Lett. 2018 Nov 7;9(12):1230-1234. doi: 10.1021/acsmedchemlett.8b00382. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613331 Free PMC article.
Emergence and Targeting of Acquired and Hereditary Resistance to Multikinase RET Inhibition in Patients With RET-Altered Cancer.
Wirth LJ, Kohno T, Udagawa H, Matsumoto S, Ishii G, Ebata K, Tuch BB, Zhu EY, Nguyen M, Smith S, Hanson LM, Burkard MR, Cable L, Blake JF, Condroski KR, Brandhuber BJ, Andrews S, Rothenberg SM, Goto K. Wirth LJ, et al. Among authors: hanson lm. JCO Precis Oncol. 2019 Sep 11;3:PO.19.00189. doi: 10.1200/PO.19.00189. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32923848 Free PMC article. No abstract available.
Discovery of 5-Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors.
Elsayed MSA, Blake JF, Boys ML, Brown E, Chapsal BD, Chicarelli MJ, Cook AW, Fell JB, Fischer JP, Hanson L, Lemieux C, Martinson MC, McCown J, McNulty OT, Mejia MJ, Neitzel NA, Otten JN, Rodriguez ME, Wilcox D, Wong CE, Zhou Y, Hinklin RJ. Elsayed MSA, et al. Among authors: hanson l. ACS Med Chem Lett. 2023 Nov 15;14(12):1673-1681. doi: 10.1021/acsmedchemlett.3c00310. eCollection 2023 Dec 14. ACS Med Chem Lett. 2023. PMID: 38116446 Free PMC article.
A Pilot Randomized Controlled Trial of Families Addressing Cancer Together for Parents With Cancer: Feasibility, Acceptability, and Preliminary Effects.
Nakamura ZM, Deal AM, Yopp JM, Wardell AC, Manning M, Pak P, Cassidy A, Hanson LC, Jung A, Song MK, Valle CG, Walker C, Won H, Park EM, Rosenstein DL. Nakamura ZM, et al. Among authors: hanson lc. Psychooncology. 2025 Jan;34(1):e70072. doi: 10.1002/pon.70072. Psychooncology. 2025. PMID: 39763133 Clinical Trial.
Case Report of Vaginal Breech Birth.
Malloy E, Hanson L, Oliver KS, Rivelli A, Belotti C, Bauer CC. Malloy E, et al. Among authors: hanson l. J Obstet Gynecol Neonatal Nurs. 2024 Dec 30:S0884-2175(24)00350-2. doi: 10.1016/j.jogn.2024.12.005. Online ahead of print. J Obstet Gynecol Neonatal Nurs. 2024. PMID: 39746657
Opioid use, prescribing patterns, and disposal after surgical procedures.
Hanson LB, Hummel PS, Kokko-Ludemann JW, Lee K, Polgreen LA. Hanson LB, et al. Explor Res Clin Soc Pharm. 2024 Jul 14;15:100476. doi: 10.1016/j.rcsop.2024.100476. eCollection 2024 Sep. Explor Res Clin Soc Pharm. 2024. PMID: 39712865 Free PMC article. No abstract available.
1,595 results