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ESKAPEing the labyrinth of antibacterial discovery.
Tommasi R, Brown DG, Walkup GK, Manchester JI, Miller AA. Tommasi R, et al. Among authors: miller aa. Nat Rev Drug Discov. 2015 Aug;14(8):529-42. doi: 10.1038/nrd4572. Epub 2015 Jul 3. Nat Rev Drug Discov. 2015. PMID: 26139286 Review.
ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii.
Durand-Réville TF, Guler S, Comita-Prevoir J, Chen B, Bifulco N, Huynh H, Lahiri S, Shapiro AB, McLeod SM, Carter NM, Moussa SH, Velez-Vega C, Olivier NB, McLaughlin R, Gao N, Thresher J, Palmer T, Andrews B, Giacobbe RA, Newman JV, Ehmann DE, de Jonge B, O'Donnell J, Mueller JP, Tommasi RA, Miller AA. Durand-Réville TF, et al. Among authors: miller aa. Nat Microbiol. 2017 Jun 30;2:17104. doi: 10.1038/nmicrobiol.2017.104. Nat Microbiol. 2017. PMID: 28665414
Frequency and Mechanism of Spontaneous Resistance to Sulbactam Combined with the Novel β-Lactamase Inhibitor ETX2514 in Clinical Isolates of Acinetobacter baumannii.
McLeod SM, Shapiro AB, Moussa SH, Johnstone M, McLaughlin RE, de Jonge BLM, Miller AA. McLeod SM, et al. Among authors: miller aa. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e01576-17. doi: 10.1128/AAC.01576-17. Print 2018 Feb. Antimicrob Agents Chemother. 2018. PMID: 29133555 Free PMC article.
345 results