Brasier AR - Search Results

1

Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation.

Liu Z, Chen H, Wang P, Li Y, Wold EA, Leonard PG, Joseph S, Brasier AR, Tian B, Zhou J. Liu Z, et al. Among authors: brasier ar. J Med Chem. 2020 May 28;63(10):5242-5256. doi: 10.1021/acs.jmedchem.0c00035. Epub 2020 Apr 22. J Med Chem. 2020. PMID: 32255647 Free PMC article.

2

Identification of NF-kappaB-dependent gene networks in respiratory syncytial virus-infected cells.

Tian B, Zhang Y, Luxon BA, Garofalo RP, Casola A, Sinha M, Brasier AR. Tian B, et al. Among authors: brasier ar. J Virol. 2002 Jul;76(13):6800-14. doi: 10.1128/jvi.76.13.6800-6814.2002. J Virol. 2002. PMID: 12050393 Free PMC article.

3

Ribavirin treatment up-regulates antiviral gene expression via the interferon-stimulated response element in respiratory syncytial virus-infected epithelial cells.

Zhang Y, Jamaluddin M, Wang S, Tian B, Garofalo RP, Casola A, Brasier AR. Zhang Y, et al. Among authors: brasier ar. J Virol. 2003 May;77(10):5933-47. doi: 10.1128/jvi.77.10.5933-5947.2003. J Virol. 2003. PMID: 12719586 Free PMC article.

4

Identification of a nuclear factor kappa B-dependent gene network.

Tian B, Brasier AR. Tian B, et al. Among authors: brasier ar. Recent Prog Horm Res. 2003;58:95-130. doi: 10.1210/rp.58.1.95. Recent Prog Horm Res. 2003. PMID: 12795416 Review.

5

Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling.

Tian B, Nowak DE, Jamaluddin M, Wang S, Brasier AR. Tian B, et al. Among authors: brasier ar. J Biol Chem. 2005 Apr 29;280(17):17435-48. doi: 10.1074/jbc.M500437200. Epub 2005 Feb 18. J Biol Chem. 2005. PMID: 15722553 Free article.

6

A TNF-induced gene expression program under oscillatory NF-kappaB control.

Tian B, Nowak DE, Brasier AR. Tian B, et al. Among authors: brasier ar. BMC Genomics. 2005 Sep 28;6:137. doi: 10.1186/1471-2164-6-137. BMC Genomics. 2005. PMID: 16191192 Free PMC article.

7

Two-step cross-linking method for identification of NF-kappaB gene network by chromatin immunoprecipitation.

Nowak DE, Tian B, Brasier AR. Nowak DE, et al. Among authors: brasier ar. Biotechniques. 2005 Nov;39(5):715-25. doi: 10.2144/000112014. Biotechniques. 2005. PMID: 16315372 Free article.

8

TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway.

Jamaluddin M, Wang S, Boldogh I, Tian B, Brasier AR. Jamaluddin M, et al. Among authors: brasier ar. Cell Signal. 2007 Jul;19(7):1419-33. doi: 10.1016/j.cellsig.2007.01.020. Epub 2007 Jan 25. Cell Signal. 2007. PMID: 17317104

9

RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes.

Nowak DE, Tian B, Jamaluddin M, Boldogh I, Vergara LA, Choudhary S, Brasier AR. Nowak DE, et al. Among authors: brasier ar. Mol Cell Biol. 2008 Jun;28(11):3623-38. doi: 10.1128/MCB.01152-07. Epub 2008 Mar 24. Mol Cell Biol. 2008. PMID: 18362169 Free PMC article.

10

Respiratory syncytial virus infection induces a reactive oxygen species-MSK1-phospho-Ser-276 RelA pathway required for cytokine expression.

Jamaluddin M, Tian B, Boldogh I, Garofalo RP, Brasier AR. Jamaluddin M, et al. Among authors: brasier ar. J Virol. 2009 Oct;83(20):10605-15. doi: 10.1128/JVI.01090-09. Epub 2009 Aug 12. J Virol. 2009. PMID: 19706715 Free PMC article.

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