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Page 1
Intercalated cell BKα subunit is required for flow-induced K+ secretion.
Carrisoza-Gaytan R, Ray EC, Flores D, Marciszyn AL, Wu P, Liu L, Subramanya AR, Wang W, Sheng S, Nkashama LJ, Chen J, Jackson EK, Mutchler SM, Heja S, Kohan DE, Satlin LM, Kleyman TR. Carrisoza-Gaytan R, et al. Among authors: subramanya ar. JCI Insight. 2020 Apr 7;5(8):e130553. doi: 10.1172/jci.insight.130553. JCI Insight. 2020. PMID: 32255763 Free PMC article.
Regulation of large-conductance Ca2+-activated K+ channels by WNK4 kinase.
Wang Z, Subramanya AR, Satlin LM, Pastor-Soler NM, Carattino MD, Kleyman TR. Wang Z, et al. Among authors: subramanya ar. Am J Physiol Cell Physiol. 2013 Oct 15;305(8):C846-53. doi: 10.1152/ajpcell.00133.2013. Epub 2013 Jul 24. Am J Physiol Cell Physiol. 2013. PMID: 23885063 Free PMC article.
Cell-specific regulation of L-WNK1 by dietary K.
Webb TN, Carrisoza-Gaytan R, Montalbetti N, Rued A, Roy A, Socovich AM, Subramanya AR, Satlin LM, Kleyman TR, Carattino MD. Webb TN, et al. Among authors: subramanya ar. Am J Physiol Renal Physiol. 2016 Jan 1;310(1):F15-26. doi: 10.1152/ajprenal.00226.2015. Epub 2015 Oct 14. Am J Physiol Renal Physiol. 2016. PMID: 26662201 Free PMC article.
Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent.
Boyd-Shiwarski CR, Shiwarski DJ, Roy A, Namboodiri HN, Nkashama LJ, Xie J, McClain KL, Marciszyn A, Kleyman TR, Tan RJ, Stolz DB, Puthenveedu MA, Huang CL, Subramanya AR. Boyd-Shiwarski CR, et al. Among authors: subramanya ar. Mol Biol Cell. 2018 Feb 15;29(4):499-509. doi: 10.1091/mbc.E17-08-0529. Epub 2017 Dec 13. Mol Biol Cell. 2018. PMID: 29237822 Free PMC article.
Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus.
Jobbagy S, Vitturi DA, Salvatore SR, Pires MF, Rowart P, Emlet DR, Ross M, Hahn S, St Croix C, Wendell SG, Subramanya AR, Straub AC, Tan RJ, Schopfer FJ. Jobbagy S, et al. Among authors: subramanya ar. JCI Insight. 2020 Jan 16;5(1):e128578. doi: 10.1172/jci.insight.128578. JCI Insight. 2020. PMID: 31941842 Free PMC article.
Effects of extreme potassium stress on blood pressure and renal tubular sodium transport.
Boyd-Shiwarski CR, Weaver CJ, Beacham RT, Shiwarski DJ, Connolly KA, Nkashama LJ, Mutchler SM, Griffiths SE, Knoell SA, Sebastiani RS, Ray EC, Marciszyn AL, Subramanya AR. Boyd-Shiwarski CR, et al. Among authors: subramanya ar. Am J Physiol Renal Physiol. 2020 Jun 1;318(6):F1341-F1356. doi: 10.1152/ajprenal.00527.2019. Epub 2020 Apr 13. Am J Physiol Renal Physiol. 2020. PMID: 32281415 Free PMC article.
L-WNK1 is required for BK channel activation in intercalated cells.
Ray EC, Carrisoza-Gaytan R, Al-Bataineh M, Marciszyn AL, Nkashama LJ, Chen J, Winfrey A, Griffiths S, Lam TR, Flores D, Wu P, Wang W, Huang CL, Subramanya AR, Kleyman TR, Satlin LM. Ray EC, et al. Among authors: subramanya ar. Am J Physiol Renal Physiol. 2021 Aug 1;321(2):F245-F254. doi: 10.1152/ajprenal.00472.2020. Epub 2021 Jul 6. Am J Physiol Renal Physiol. 2021. PMID: 34229479 Free PMC article.
The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice.
Porter AW, Nguyen DN, Clayton DR, Ruiz WG, Mutchler SM, Ray EC, Marciszyn AL, Nkashama LJ, Subramanya AR, Gingras S, Kleyman TR, Apodaca G, Hendershot LM, Brodsky JL, Buck TM. Porter AW, et al. Among authors: subramanya ar. JCI Insight. 2022 Mar 8;7(5):e151869. doi: 10.1172/jci.insight.151869. JCI Insight. 2022. PMID: 35104250 Free PMC article.
WNK kinases sense molecular crowding and rescue cell volume via phase separation.
Boyd-Shiwarski CR, Shiwarski DJ, Griffiths SE, Beacham RT, Norrell L, Morrison DE, Wang J, Mann J, Tennant W, Anderson EN, Franks J, Calderon M, Connolly KA, Cheema MU, Weaver CJ, Nkashama LJ, Weckerly CC, Querry KE, Pandey UB, Donnelly CJ, Sun D, Rodan AR, Subramanya AR. Boyd-Shiwarski CR, et al. Among authors: subramanya ar. Cell. 2022 Nov 23;185(24):4488-4506.e20. doi: 10.1016/j.cell.2022.09.042. Epub 2022 Oct 31. Cell. 2022. PMID: 36318922 Free PMC article.
44 results