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Systems genetics applications in metabolism research.
Seldin M, Yang X, Lusis AJ. Seldin M, et al. Nat Metab. 2019 Nov;1(11):1038-1050. doi: 10.1038/s42255-019-0132-x. Epub 2019 Oct 21. Nat Metab. 2019. PMID: 32259026 Free PMC article. Review.
Multi-omics approaches to disease.
Hasin Y, Seldin M, Lusis A. Hasin Y, et al. Among authors: seldin m. Genome Biol. 2017 May 5;18(1):83. doi: 10.1186/s13059-017-1215-1. Genome Biol. 2017. PMID: 28476144 Free PMC article. Review.
Epigenome-wide association in adipose tissue from the METSIM cohort.
Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, Lusis AJ, Pellegrini M. Orozco LD, et al. Among authors: seldin m. Hum Mol Genet. 2018 May 15;27(10):1830-1846. doi: 10.1093/hmg/ddy093. Hum Mol Genet. 2018. PMID: 29566149 Free PMC article.
Epigenome-wide association in adipose tissue from the METSIM cohort.
Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, Lusis AJ, Pellegrini M. Orozco LD, et al. Among authors: seldin m. Hum Mol Genet. 2018 Jul 15;27(14):2586. doi: 10.1093/hmg/ddy205. Hum Mol Genet. 2018. PMID: 29893869 Free PMC article. No abstract available.
Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans.
Lin LY, Chun Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, Wang Y, Lusis AJ, Wang JJ, Huertas-Vazquez A. Lin LY, et al. Among authors: seldin m. G3 (Bethesda). 2018 Nov 6;8(11):3499-3506. doi: 10.1534/g3.118.200655. G3 (Bethesda). 2018. PMID: 30201759 Free PMC article.
FAM13A affects body fat distribution and adipocyte function.
Fathzadeh M, Li J, Rao A, Cook N, Chennamsetty I, Seldin M, Zhou X, Sangwung P, Gloudemans MJ, Keller M, Attie A, Yang J, Wabitsch M, Carcamo-Orive I, Tada Y, Lusis AJ, Shin MK, Molony CM, McLaughlin T, Reaven G, Montgomery SB, Reilly D, Quertermous T, Ingelsson E, Knowles JW. Fathzadeh M, et al. Among authors: seldin m. Nat Commun. 2020 Mar 19;11(1):1465. doi: 10.1038/s41467-020-15291-z. Nat Commun. 2020. PMID: 32193374 Free PMC article.
Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury.
Yokota T, McCourt J, Ma F, Ren S, Li S, Kim TH, Kurmangaliyev YZ, Nasiri R, Ahadian S, Nguyen T, Tan XHM, Zhou Y, Wu R, Rodriguez A, Cohn W, Wang Y, Whitelegge J, Ryazantsev S, Khademhosseini A, Teitell MA, Chiou PY, Birk DE, Rowat AC, Crosbie RH, Pellegrini M, Seldin M, Lusis AJ, Deb A. Yokota T, et al. Among authors: seldin m. Cell. 2020 Aug 6;182(3):545-562.e23. doi: 10.1016/j.cell.2020.06.030. Epub 2020 Jul 3. Cell. 2020. PMID: 32621799 Free PMC article.
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling.
Zhou Z, Moore TM, Drew BG, Ribas V, Wanagat J, Civelek M, Segawa M, Wolf DM, Norheim F, Seldin MM, Strumwasser AR, Whitney KA, Lester E, Reddish BR, Vergnes L, Reue K, Rajbhandari P, Tontonoz P, Lee J, Mahata SK, Hewitt SC, Shirihai O, Gastonbury C, Small KS, Laakso M, Jensen J, Lee S, Drevon CA, Korach KS, Lusis AJ, Hevener AL. Zhou Z, et al. Among authors: seldin mm. Sci Transl Med. 2020 Aug 5;12(555):eaax8096. doi: 10.1126/scitranslmed.aax8096. Sci Transl Med. 2020. PMID: 32759275 Free PMC article.
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis.
Norheim F, Chella Krishnan K, Bjellaas T, Vergnes L, Pan C, Parks BW, Meng Y, Lang J, Ward JA, Reue K, Mehrabian M, Gundersen TE, Péterfy M, Dalen KT, Drevon CA, Hui ST, Lusis AJ, Seldin MM. Norheim F, et al. Among authors: seldin mm. Mol Syst Biol. 2021 Jan;17(1):e9684. doi: 10.15252/msb.20209684. Mol Syst Biol. 2021. PMID: 33417276 Free PMC article.
Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.
Hartiala JA, Han Y, Jia Q, Hilser JR, Huang P, Gukasyan J, Schwartzman WS, Cai Z, Biswas S, Trégouët DA, Smith NL; INVENT Consortium; CHARGE Consortium Hemostasis Working Group; GENIUS-CHD Consortium; Seldin M, Pan C, Mehrabian M, Lusis AJ, Bazeley P, Sun YV, Liu C, Quyyumi AA, Scholz M, Thiery J, Delgado GE, Kleber ME, März W, Howe LJ, Asselbergs FW, van Vugt M, Vlachojannis GJ, Patel RS, Lyytikäinen LP, Kähönen M, Lehtimäki T, Nieminen TVM, Kuukasjärvi P, Laurikka JO, Chang X, Heng CK, Jiang R, Kraus WE, Hauser ER, Ferguson JF, Reilly MP, Ito K, Koyama S, Kamatani Y, Komuro I; Biobank Japan; Stolze LK, Romanoski CE, Khan MD, Turner AW, Miller CL, Aherrahrou R, Civelek M, Ma L, Björkegren JLM, Kumar SR, Tang WHW, Hazen SL, Allayee H. Hartiala JA, et al. Among authors: seldin m. Eur Heart J. 2021 Mar 1;42(9):919-933. doi: 10.1093/eurheartj/ehaa1040. Eur Heart J. 2021. PMID: 33532862 Free PMC article.
495 results