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Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.
Li Q, Sun Y, Jarugumilli GK, Liu S, Dang K, Cotton JL, Xiol J, Chan PY, DeRan M, Ma L, Li R, Zhu LJ, Li JH, Leiter AB, Ip YT, Camargo FD, Luo X, Johnson RL, Wu X, Mao J. Li Q, et al. Among authors: deran m. Cell Stem Cell. 2020 May 7;26(5):675-692.e8. doi: 10.1016/j.stem.2020.03.002. Epub 2020 Apr 6. Cell Stem Cell. 2020. PMID: 32259481 Free PMC article.
YAP-dependent proliferation by a small molecule targeting annexin A2.
Shalhout SZ, Yang PY, Grzelak EM, Nutsch K, Shao S, Zambaldo C, Iaconelli J, Ibrahim L, Stanton C, Chadwick SR, Chen E, DeRan M, Li S, Hull M, Wu X, Chatterjee AK, Shen W, Camargo FD, Schultz PG, Bollong MJ. Shalhout SZ, et al. Among authors: deran m. Nat Chem Biol. 2021 Jul;17(7):767-775. doi: 10.1038/s41589-021-00755-0. Epub 2021 Mar 15. Nat Chem Biol. 2021. PMID: 33723431
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis.
Eelen G, Dubois C, Cantelmo AR, Goveia J, Brüning U, DeRan M, Jarugumilli G, van Rijssel J, Saladino G, Comitani F, Zecchin A, Rocha S, Chen R, Huang H, Vandekeere S, Kalucka J, Lange C, Morales-Rodriguez F, Cruys B, Treps L, Ramer L, Vinckier S, Brepoels K, Wyns S, Souffreau J, Schoonjans L, Lamers WH, Wu Y, Haustraete J, Hofkens J, Liekens S, Cubbon R, Ghesquière B, Dewerchin M, Gervasio FL, Li X, van Buul JD, Wu X, Carmeliet P. Eelen G, et al. Among authors: deran m. Nature. 2018 Sep;561(7721):63-69. doi: 10.1038/s41586-018-0466-7. Epub 2018 Aug 29. Nature. 2018. PMID: 30158707 Free article.
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma.
Chen EY, DeRan MT, Ignatius MS, Grandinetti KB, Clagg R, McCarthy KM, Lobbardi RM, Brockmann J, Keller C, Wu X, Langenau DM. Chen EY, et al. Among authors: deran mt. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5349-54. doi: 10.1073/pnas.1317731111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706870 Free PMC article.
17 results