Sarno A - Search Results

1

HDACi mediate UNG2 depletion, dysregulated genomic uracil and altered expression of oncoproteins and tumor suppressors in B- and T-cell lines.

Iveland TS, Hagen L, Sharma A, Sousa MML, Sarno A, Wollen KL, Liabakk NB, Slupphaug G. Iveland TS, et al. Among authors: sarno a. J Transl Med. 2020 Apr 7;18(1):159. doi: 10.1186/s12967-020-02318-8. J Transl Med. 2020. PMID: 32264925 Free PMC article.

2

Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse.

Doseth B, Visnes T, Wallenius A, Ericsson I, Sarno A, Pettersen HS, Flatberg A, Catterall T, Slupphaug G, Krokan HE, Kavli B. Doseth B, et al. Among authors: sarno a. J Biol Chem. 2011 May 13;286(19):16669-80. doi: 10.1074/jbc.M111.230052. Epub 2011 Mar 23. J Biol Chem. 2011. PMID: 21454529 Free PMC article.

3

An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells.

Sousa MM, Zub KA, Aas PA, Hanssen-Bauer A, Demirovic A, Sarno A, Tian E, Liabakk NB, Slupphaug G. Sousa MM, et al. Among authors: sarno a. PLoS One. 2013;8(2):e55493. doi: 10.1371/journal.pone.0055493. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405159 Free PMC article.

4

A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported.

Galashevskaya A, Sarno A, Vågbø CB, Aas PA, Hagen L, Slupphaug G, Krokan HE. Galashevskaya A, et al. Among authors: sarno a. DNA Repair (Amst). 2013 Sep;12(9):699-706. doi: 10.1016/j.dnarep.2013.05.002. Epub 2013 Jun 3. DNA Repair (Amst). 2013. PMID: 23742752 Free article.

5

AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.

Pettersen HS, Galashevskaya A, Doseth B, Sousa MM, Sarno A, Visnes T, Aas PA, Liabakk NB, Slupphaug G, Sætrom P, Kavli B, Krokan HE. Pettersen HS, et al. Among authors: sarno a. DNA Repair (Amst). 2015 Jan;25:60-71. doi: 10.1016/j.dnarep.2014.11.006. Epub 2014 Nov 24. DNA Repair (Amst). 2015. PMID: 25486549 Free article.

6

Modulation of cell metabolic pathways and oxidative stress signaling contribute to acquired melphalan resistance in multiple myeloma cells.

Zub KA, Sousa MM, Sarno A, Sharma A, Demirovic A, Rao S, Young C, Aas PA, Ericsson I, Sundan A, Jensen ON, Slupphaug G. Zub KA, et al. Among authors: sarno a. PLoS One. 2015 Mar 13;10(3):e0119857. doi: 10.1371/journal.pone.0119857. eCollection 2015. PLoS One. 2015. PMID: 25769101 Free PMC article.

7

Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil.

Sarno A, Lundbæk M, Liabakk NB, Aas PA, Mjelle R, Hagen L, Sousa MML, Krokan HE, Kavli B. Sarno A, et al. Nucleic Acids Res. 2019 May 21;47(9):4569-4585. doi: 10.1093/nar/gkz145. Nucleic Acids Res. 2019. PMID: 30838409 Free PMC article.

8

Correction to: HDACi mediate UNG2 depletion, dysregulated genomic uracil and altered expression of oncoproteins and tumor suppressors in B- and T-cell lines.

Iveland TS, Hagen L, Sharma A, Sousa MML, Sarno A, Wollen KL, Liabakk NB, Slupphaug G. Iveland TS, et al. Among authors: sarno a. J Transl Med. 2021 Jun 4;19(1):243. doi: 10.1186/s12967-021-02896-1. J Transl Med. 2021. PMID: 34088330 Free PMC article. No abstract available.

9

RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork.

Hayran AB, Liabakk NB, Aas PA, Kusnierczyk A, Vågbø CB, Sarno A, Iveland TS, Chawla K, Zahn A, Di Noia JM, Slupphaug G, Kavli B. Hayran AB, et al. Among authors: sarno a. Nucleic Acids Res. 2024 Jan 25;52(2):784-800. doi: 10.1093/nar/gkad1115. Nucleic Acids Res. 2024. PMID: 38000394 Free PMC article.

10

Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH.

Obermann T, Sakshaug T, Kanagaraj VV, Abentung A, Sousa MML, Hagen L, Sarno A, Bjørås M, Scheffler K. Obermann T, et al. Among authors: sarno a. Redox Biol. 2024 Dec 5;79:103461. doi: 10.1016/j.redox.2024.103461. Online ahead of print. Redox Biol. 2024. PMID: 39662289 Free PMC article.

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