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IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection.
Kwock JT, Handfield C, Suwanpradid J, Hoang P, McFadden MJ, Labagnara KF, Floyd L, Shannon J, Uppala R, Sarkar MK, Gudjonsson JE, Corcoran DL, Lazear HM, Sempowski G, Horner SM, MacLeod AS. Kwock JT, et al. Among authors: sempowski g. Sci Adv. 2020 Apr 1;6(14):eaay3245. doi: 10.1126/sciadv.aay3245. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32270034 Free PMC article.
Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model.
Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE Jr, de Silva AM, Ting JP. Callaway JB, et al. Among authors: sempowski gd. PLoS One. 2015 Aug 24;10(8):e0136708. doi: 10.1371/journal.pone.0136708. eCollection 2015. PLoS One. 2015. PMID: 26301593 Free PMC article.
NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses.
Guo H, König R, Deng M, Riess M, Mo J, Zhang L, Petrucelli A, Yoh SM, Barefoot B, Samo M, Sempowski GD, Zhang A, Colberg-Poley AM, Feng H, Lemon SM, Liu Y, Zhang Y, Wen H, Zhang Z, Damania B, Tsao LC, Wang Q, Su L, Duncan JA, Chanda SK, Ting JP. Guo H, et al. Cell Host Microbe. 2016 Apr 13;19(4):515-528. doi: 10.1016/j.chom.2016.03.001. Cell Host Microbe. 2016. PMID: 27078069 Free PMC article.
Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination.
Pardi N, Hogan MJ, Pelc RS, Muramatsu H, Andersen H, DeMaso CR, Dowd KA, Sutherland LL, Scearce RM, Parks R, Wagner W, Granados A, Greenhouse J, Walker M, Willis E, Yu JS, McGee CE, Sempowski GD, Mui BL, Tam YK, Huang YJ, Vanlandingham D, Holmes VM, Balachandran H, Sahu S, Lifton M, Higgs S, Hensley SE, Madden TD, Hope MJ, Karikó K, Santra S, Graham BS, Lewis MG, Pierson TC, Haynes BF, Weissman D. Pardi N, et al. Among authors: sempowski gd. Nature. 2017 Mar 9;543(7644):248-251. doi: 10.1038/nature21428. Epub 2017 Feb 2. Nature. 2017. PMID: 28151488 Free PMC article.
Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.
McClain MT, Constantine FJ, Henao R, Liu Y, Tsalik EL, Burke TW, Steinbrink JM, Petzold E, Nicholson BP, Rolfe R, Kraft BD, Kelly MS, Saban DR, Yu C, Shen X, Ko EM, Sempowski GD, Denny TN, Ginsburg GS, Woods CW. McClain MT, et al. Nat Commun. 2021 Feb 17;12(1):1079. doi: 10.1038/s41467-021-21289-y. Nat Commun. 2021. PMID: 33597532 Free PMC article.
Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test.
Heggestad JT, Kinnamon DS, Olson LB, Liu J, Kelly G, Wall SA, Oshabaheebwa S, Quinn Z, Fontes CM, Joh DY, Hucknall AM, Pieper C, Anderson JG, Naqvi IA, Chen L, Que LG, Oguin T 3rd, Nair SK, Sullenger BA, Woods CW, Burke TW, Sempowski GD, Kraft BD, Chilkoti A. Heggestad JT, et al. Among authors: sempowski gd. Sci Adv. 2021 Jun 25;7(26):eabg4901. doi: 10.1126/sciadv.abg4901. Print 2021 Jun. Sci Adv. 2021. PMID: 34172447 Free PMC article.
204 results