Auchampach JA - Search Results

1

Truncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A₃ Adenosine Receptors: Affinity Enhancement by N⁶-(2-Phenylethyl) Substitution.

Tosh DK, Salmaso V, Rao H, Bitant A, Fisher CL, Lieberman DI, Vorbrüggen H, Reitman ML, Gavrilova O, Gao ZG, Auchampach JA, Jacobson KA. Tosh DK, et al. Among authors: auchampach ja. J Med Chem. 2020 Apr 23;63(8):4334-4348. doi: 10.1021/acs.jmedchem.0c00235. Epub 2020 Apr 9. J Med Chem. 2020. PMID: 32271569 Free PMC article.

2

The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-3'-aminoadenosine-5'-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel.

Wan TC, Ge ZD, Tampo A, Mio Y, Bienengraeber MW, Tracey WR, Gross GJ, Kwok WM, Auchampach JA. Wan TC, et al. Among authors: auchampach ja. J Pharmacol Exp Ther. 2008 Jan;324(1):234-43. doi: 10.1124/jpet.107.127480. Epub 2007 Sep 28. J Pharmacol Exp Ther. 2008. PMID: 17906066 Free PMC article.

3

Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists.

Melman A, Gao ZG, Kumar D, Wan TC, Gizewski E, Auchampach JA, Jacobson KA. Melman A, et al. Among authors: auchampach ja. Bioorg Med Chem Lett. 2008 May 1;18(9):2813-9. doi: 10.1016/j.bmcl.2008.04.001. Epub 2008 Apr 4. Bioorg Med Chem Lett. 2008. PMID: 18424135 Free PMC article.

4

Synthesis and pharmacological characterization of [(125)I]MRS5127, a high affinity, selective agonist radioligand for the A3 adenosine receptor.

Auchampach JA, Gizewski ET, Wan TC, de Castro S, Brown GG Jr, Jacobson KA. Auchampach JA, et al. Biochem Pharmacol. 2010 Apr 1;79(7):967-73. doi: 10.1016/j.bcp.2009.11.009. Epub 2009 Nov 14. Biochem Pharmacol. 2010. PMID: 19917269 Free PMC article.

5

Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A₃ adenosine receptor.

Du L, Gao ZG, Nithipatikom K, Ijzerman AP, Veldhoven JP, Jacobson KA, Gross GJ, Auchampach JA. Du L, et al. Among authors: auchampach ja. J Pharmacol Exp Ther. 2012 Jan;340(1):210-7. doi: 10.1124/jpet.111.187559. Epub 2011 Oct 19. J Pharmacol Exp Ther. 2012. PMID: 22011434 Free PMC article.

6

Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts.

Wan TC, Tosh DK, Du L, Gizewski ET, Jacobson KA, Auchampach JA. Wan TC, et al. Among authors: auchampach ja. BMC Pharmacol. 2011 Oct 31;11:11. doi: 10.1186/1471-2210-11-11. BMC Pharmacol. 2011. PMID: 22039965 Free PMC article.

7

Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions.

Tosh DK, Deflorian F, Phan K, Gao ZG, Wan TC, Gizewski E, Auchampach JA, Jacobson KA. Tosh DK, et al. Among authors: auchampach ja. J Med Chem. 2012 May 24;55(10):4847-60. doi: 10.1021/jm300396n. Epub 2012 May 16. J Med Chem. 2012. PMID: 22559880 Free PMC article.

8

Characterization by flow cytometry of fluorescent, selective agonist probes of the A(3) adenosine receptor.

Kozma E, Gizewski ET, Tosh DK, Squarcialupi L, Auchampach JA, Jacobson KA. Kozma E, et al. Among authors: auchampach ja. Biochem Pharmacol. 2013 Apr 15;85(8):1171-81. doi: 10.1016/j.bcp.2013.01.021. Epub 2013 Jan 31. Biochem Pharmacol. 2013. PMID: 23376019 Free PMC article.

9

Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain.

Paoletta S, Tosh DK, Finley A, Gizewski ET, Moss SM, Gao ZG, Auchampach JA, Salvemini D, Jacobson KA. Paoletta S, et al. Among authors: auchampach ja. J Med Chem. 2013 Jul 25;56(14):5949-63. doi: 10.1021/jm4007966. Epub 2013 Jul 3. J Med Chem. 2013. PMID: 23789857 Free PMC article.

10

In vivo phenotypic screening for treating chronic neuropathic pain: modification of C2-arylethynyl group of conformationally constrained A3 adenosine receptor agonists.

Tosh DK, Finley A, Paoletta S, Moss SM, Gao ZG, Gizewski ET, Auchampach JA, Salvemini D, Jacobson KA. Tosh DK, et al. Among authors: auchampach ja. J Med Chem. 2014 Dec 11;57(23):9901-14. doi: 10.1021/jm501021n. Epub 2014 Nov 25. J Med Chem. 2014. PMID: 25422861 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

104 results

Search Page

Filters