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Knockout of the Murine Ortholog to the Human 9p21 Coronary Artery Disease Locus Leads to Smooth Muscle Cell Proliferation, Vascular Calcification, and Advanced Atherosclerosis.
Kojima Y, Ye J, Nanda V, Wang Y, Flores AM, Jarr KU, Tsantilas P, Guo L, Finn AV, Virmani R, Leeper NJ. Kojima Y, et al. Among authors: leeper nj. Circulation. 2020 Apr 14;141(15):1274-1276. doi: 10.1161/CIRCULATIONAHA.119.043413. Epub 2020 Apr 13. Circulation. 2020. PMID: 32282248 Free PMC article. No abstract available.
Integrative multi-ancestry genetic analysis of gene regulation in coronary arteries prioritizes disease risk loci.
Hodonsky CJ, Turner AW, Khan MD, Barrientos NB, Methorst R, Ma L, Lopez NG, Mosquera JV, Auguste G, Farber E, Ma WF, Wong D, Onengut-Gumuscu S, Kavousi M, Peyser PA, van der Laan SW, Leeper NJ, Kovacic JC, Björkegren JLM, Miller CL. Hodonsky CJ, et al. Among authors: leeper nj. medRxiv [Preprint]. 2023 Feb 14:2023.02.09.23285622. doi: 10.1101/2023.02.09.23285622. medRxiv. 2023. Update in: Cell Genom. 2024 Jan 10;4(1):100465. doi: 10.1016/j.xgen.2023.100465 PMID: 36824883 Free PMC article. Updated. Preprint.
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis.
Chun HJ, Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T. Chun HJ, et al. Among authors: leeper nj. J Clin Invest. 2008 Oct;118(10):3343-54. doi: 10.1172/JCI34871. J Clin Invest. 2008. PMID: 18769630 Free PMC article.
Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T. Leeper NJ, et al. Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1329-35. doi: 10.1152/ajpheart.01341.2008. Epub 2009 Mar 20. Am J Physiol Heart Circ Physiol. 2009. PMID: 19304942 Free PMC article.
Genetics of peripheral artery disease.
Leeper NJ, Kullo IJ, Cooke JP. Leeper NJ, et al. Circulation. 2012 Jun 26;125(25):3220-8. doi: 10.1161/CIRCULATIONAHA.111.033878. Circulation. 2012. PMID: 22733336 Free PMC article. Review. No abstract available.
Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Leeper NJ, Raiesdana A, Kojima Y, Kundu RK, Cheng H, Maegdefessel L, Toh R, Ahn GO, Ali ZA, Anderson DR, Miller CL, Roberts SC, Spin JM, de Almeida PE, Wu JC, Xu B, Cheng K, Quertermous M, Kundu S, Kortekaas KE, Berzin E, Downing KP, Dalman RL, Tsao PS, Schadt EE, Owens GK, Quertermous T. Leeper NJ, et al. Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):e1-e10. doi: 10.1161/ATVBAHA.112.300399. Epub 2012 Nov 15. Arterioscler Thromb Vasc Biol. 2013. PMID: 23162013 Free PMC article.
155 results