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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. Duewell P, et al. Among authors: lien e. Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938. Nature. 2010. PMID: 20428172 Free PMC article.
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A. Sandanger Ø, et al. Among authors: lien e. Cardiovasc Res. 2013 Jul 1;99(1):164-74. doi: 10.1093/cvr/cvt091. Epub 2013 Apr 10. Cardiovasc Res. 2013. PMID: 23580606
NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction.
Sokolova M, Sahraoui A, Høyem M, Øgaard J, Lien E, Aukrust P, Yndestad A, Ranheim T, Scholz H. Sokolova M, et al. Among authors: lien e. Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E912-E923. doi: 10.1152/ajpendo.00461.2017. Epub 2018 Jul 17. Am J Physiol Endocrinol Metab. 2018. PMID: 30016155 Free article.
A Sugar Rush for Innate Immunity.
Orning P, Flo TH, Lien E. Orning P, et al. Among authors: lien e. Cell Host Microbe. 2018 Oct 10;24(4):461-463. doi: 10.1016/j.chom.2018.09.017. Cell Host Microbe. 2018. PMID: 30308148 Free PMC article.
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E. Orning P, et al. Among authors: lien e. Science. 2018 Nov 30;362(6418):1064-1069. doi: 10.1126/science.aau2818. Epub 2018 Oct 25. Science. 2018. PMID: 30361383 Free PMC article.
Streptolysin O Induces the Ubiquitination and Degradation of Pro-IL-1β.
Hancz D, Westerlund E, Valfridsson C, Aemero GM, Bastiat-Sempe B, Orning P, Lien E, Wessels MR, Persson JJ. Hancz D, et al. Among authors: lien e. J Innate Immun. 2019;11(6):457-468. doi: 10.1159/000496403. Epub 2019 Mar 19. J Innate Immun. 2019. PMID: 30889575 Free PMC article.
NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity.
Sokolova M, Sjaastad I, Louwe MC, Alfsnes K, Aronsen JM, Zhang L, Haugstad SB, Bendiksen BA, Øgaard J, Bliksøen M, Lien E, Berge RK, Aukrust P, Ranheim T, Yndestad A. Sokolova M, et al. Among authors: lien e. Front Immunol. 2019 Jul 16;10:1621. doi: 10.3389/fimmu.2019.01621. eCollection 2019. Front Immunol. 2019. PMID: 31379826 Free PMC article.
Gasdermins and their role in immunity and inflammation.
Orning P, Lien E, Fitzgerald KA. Orning P, et al. Among authors: lien e. J Exp Med. 2019 Nov 4;216(11):2453-2465. doi: 10.1084/jem.20190545. Epub 2019 Sep 23. J Exp Med. 2019. PMID: 31548300 Free PMC article. Review.
499 results