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A novel class of selective CK2 inhibitors targeting its open hinge conformation.
Dalle Vedove A, Zonta F, Zanforlin E, Demitri N, Ribaudo G, Cazzanelli G, Ongaro A, Sarno S, Zagotto G, Battistutta R, Ruzzene M, Lolli G. Dalle Vedove A, et al. Among authors: demitri n. Eur J Med Chem. 2020 Jun 1;195:112267. doi: 10.1016/j.ejmech.2020.112267. Epub 2020 Mar 25. Eur J Med Chem. 2020. PMID: 32283296
Molecular architecture of the glycogen- committed PP1/PTG holoenzyme.
Semrau MS, Giachin G, Covaceuszach S, Cassetta A, Demitri N, Storici P, Lolli G. Semrau MS, et al. Among authors: demitri n. Nat Commun. 2022 Oct 19;13(1):6199. doi: 10.1038/s41467-022-33693-z. Nat Commun. 2022. PMID: 36261419 Free PMC article.
Synthesis of some tropane-based compounds targeting colon cancer.
Samir N, George RF, Elrazaz EZ, Ayoub IM, Shalaby EM, Plaisier JR, Demitri N, Wink M. Samir N, et al. Among authors: demitri n. Future Med Chem. 2020 Dec;12(23):2123-2140. doi: 10.4155/fmc-2020-0097. Epub 2020 Nov 23. Future Med Chem. 2020. PMID: 33225729
Palladium(II)-Indenyl Complexes Bearing N-Heterocyclic Carbene (NHC) Ligands as Potent and Selective Metallodrugs toward High-Grade Serous Ovarian Cancer Models.
Bortolamiol E, Mauceri M, Piccolo R, Cavarzerani E, Demitri N, Donati C, Gandin V, Brezar SK, Kamensek U, Cemazar M, Canzonieri V, Rizzolio F, Visentin F, Scattolin T. Bortolamiol E, et al. Among authors: demitri n. J Med Chem. 2024 Aug 22;67(16):14414-14431. doi: 10.1021/acs.jmedchem.4c01203. Epub 2024 Aug 9. J Med Chem. 2024. PMID: 39119630
A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition.
Redenti S, Marcovich I, De Vita T, Pérez C, De Zorzi R, Demitri N, Perez DI, Bottegoni G, Bisignano P, Bissaro M, Moro S, Martinez A, Storici P, Spalluto G, Cavalli A, Federico S. Redenti S, et al. Among authors: demitri n. ChemMedChem. 2019 Feb 5;14(3):310-314. doi: 10.1002/cmdc.201800778. Epub 2019 Jan 15. ChemMedChem. 2019. PMID: 30548443 Free article.
127 results