Peters GJ - Search Results

1

RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier.

Sarkisjan D, Julsing JR, El Hassouni B, Honeywell RJ, Kathmann I, Matherly LH, Lee YB, Kim DJ, Peters GJ. Sarkisjan D, et al. Among authors: peters gj. Int J Mol Sci. 2020 Apr 14;21(8):2717. doi: 10.3390/ijms21082717. Int J Mol Sci. 2020. PMID: 32295203 Free PMC article.

2

Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.

Westerhof GR, Schornagel JH, Kathmann I, Jackman AL, Rosowsky A, Forsch RA, Hynes JB, Boyle FT, Peters GJ, Pinedo HM, et al. Westerhof GR, et al. Among authors: peters gj. Mol Pharmacol. 1995 Sep;48(3):459-71. Mol Pharmacol. 1995. PMID: 7565626

3

Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.

Jansen G, Mauritz RM, Assaraf YG, Sprecher H, Drori S, Kathmann I, Westerhof GR, Priest DG, Bunni M, Pinedo HM, Schornagel JH, Peters GJ. Jansen G, et al. Among authors: peters gj. Adv Enzyme Regul. 1997;37:59-76. doi: 10.1016/s0065-2571(96)00012-x. Adv Enzyme Regul. 1997. PMID: 9381986

4

A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

Jansen G, Mauritz R, Drori S, Sprecher H, Kathmann I, Bunni M, Priest DG, Noordhuis P, Schornagel JH, Pinedo HM, Peters GJ, Assaraf YG. Jansen G, et al. Among authors: peters gj. J Biol Chem. 1998 Nov 13;273(46):30189-98. doi: 10.1074/jbc.273.46.30189. J Biol Chem. 1998. PMID: 9804775 Free article.

5

Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration.

Jansen G, Barr H, Kathmann I, Bunni MA, Priest DG, Noordhuis P, Peters GJ, Assaraf YG. Jansen G, et al. Among authors: peters gj. Mol Pharmacol. 1999 Apr;55(4):761-9. Mol Pharmacol. 1999. PMID: 10101035

6

Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.

Mauritz R, Peters GJ, Priest DG, Assaraf YG, Drori S, Kathmann I, Noordhuis P, Bunni MA, Rosowsky A, Schornagel JH, Pinedo HM, Jansen G. Mauritz R, et al. Among authors: peters gj. Biochem Pharmacol. 2002 Jan 15;63(2):105-15. doi: 10.1016/s0006-2952(01)00824-3. Biochem Pharmacol. 2002. PMID: 11841783

7

Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells.

Assaraf YG, Rothem L, Hooijberg JH, Stark M, Ifergan I, Kathmann I, Dijkmans BA, Peters GJ, Jansen G. Assaraf YG, et al. Among authors: peters gj. J Biol Chem. 2003 Feb 28;278(9):6680-6. doi: 10.1074/jbc.M209186200. Epub 2002 Dec 16. J Biol Chem. 2003. PMID: 12486126 Free article.

8

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.

Hooijberg JH, Peters GJ, Assaraf YG, Kathmann I, Priest DG, Bunni MA, Veerman AJ, Scheffer GL, Kaspers GJ, Jansen G. Hooijberg JH, et al. Among authors: peters gj. Biochem Pharmacol. 2003 Mar 1;65(5):765-71. doi: 10.1016/s0006-2952(02)01615-5. Biochem Pharmacol. 2003. PMID: 12628490

9

Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1).

Hooijberg JH, Jansen G, Assaraf YG, Kathmann I, Pieters R, Laan AC, Veerman AJ, Kaspers GJ, Peters GJ. Hooijberg JH, et al. Among authors: peters gj. Biochem Pharmacol. 2004 Apr 15;67(8):1541-8. doi: 10.1016/j.bcp.2003.12.022. Biochem Pharmacol. 2004. PMID: 15041471

10

Disparate mechanisms of antifolate resistance provoked by methotrexate and its metabolite 7-hydroxymethotrexate in leukemia cells: implications for efficacy of methotrexate therapy.

Fotoohi K, Jansen G, Assaraf YG, Rothem L, Stark M, Kathmann I, Gregorczyk J, Peters GJ, Albertioni F. Fotoohi K, et al. Among authors: peters gj. Blood. 2004 Dec 15;104(13):4194-201. doi: 10.1182/blood-2004-04-1493. Epub 2004 Aug 12. Blood. 2004. PMID: 15308564 Free article.

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