Tian Y - Search Results

1

Structural modifications of indolinones bearing a pyrrole moiety and discovery of a multi-kinase inhibitor with potent antitumor activity.

Qin M, Tian Y, Han X, Cao Q, Zheng S, Liu C, Wu X, Liu L, Meng Y, Wang X, Zhang H, Hou Y. Qin M, et al. Among authors: tian y. Bioorg Med Chem. 2020 Jun 1;28(11):115486. doi: 10.1016/j.bmc.2020.115486. Epub 2020 Apr 3. Bioorg Med Chem. 2020. PMID: 32305182

2

Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

Qin M, Cao Q, Zheng S, Tian Y, Zhang H, Xie J, Xie H, Liu Y, Zhao Y, Gong P. Qin M, et al. Among authors: tian y. J Med Chem. 2019 May 9;62(9):4703-4715. doi: 10.1021/acs.jmedchem.9b00312. Epub 2019 Apr 19. J Med Chem. 2019. PMID: 30964291

3

Discovery of the programmed cell death-1/programmed cell death-ligand 1 interaction inhibitors bearing an indoline scaffold.

Qin M, Cao Q, Wu X, Liu C, Zheng S, Xie H, Tian Y, Xie J, Zhao Y, Hou Y, Zhang X, Xu B, Zhang H, Wang X. Qin M, et al. Among authors: tian y. Eur J Med Chem. 2020 Jan 15;186:111856. doi: 10.1016/j.ejmech.2019.111856. Epub 2019 Nov 9. Eur J Med Chem. 2020. PMID: 31734021

4

Ligand-based optimization to identify novel 2-aminobenzo[d]thiazole derivatives as potent sEH inhibitors with anti-inflammatory effects.

Han Y, Huang D, Xu S, Li L, Tian Y, Li S, Chen C, Li Y, Sun Y, Hou Y, Sun Y, Qin M, Gong P, Gao Z, Zhao Y. Han Y, et al. Among authors: tian y. Eur J Med Chem. 2021 Feb 15;212:113028. doi: 10.1016/j.ejmech.2020.113028. Epub 2020 Nov 17. Eur J Med Chem. 2021. PMID: 33248848

5

Discovery of 4-Arylindolines Containing a Thiazole Moiety as Potential Antitumor Agents Inhibiting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

Qin M, Meng Y, Yang H, Liu L, Zhang H, Wang S, Liu C, Wu X, Wu D, Tian Y, Hou Y, Zhao Y, Liu Y, Xu C, Wang L. Qin M, et al. Among authors: tian y. J Med Chem. 2021 May 13;64(9):5519-5534. doi: 10.1021/acs.jmedchem.0c01958. Epub 2021 May 3. J Med Chem. 2021. PMID: 33938739

6

Discovery of benzamide derivatives containing urea moiety as soluble epoxide hydrolase inhibitors.

Tian Y, Li S, Dong K, Su X, Fu S, Lv X, Duan M, Yang T, Han Y, Hu G, Liu J, Sun Y, Yue H, Sun Y, Zhang H, Du Z, Miao Z, Tong M, Liu Y, Qin M, Gong P, Hou Y, Gao Z, Zhao Y. Tian Y, et al. Bioorg Chem. 2022 Oct;127:105898. doi: 10.1016/j.bioorg.2022.105898. Epub 2022 May 24. Bioorg Chem. 2022. PMID: 35792317

7

Novel 6-methoxycarbonyl indolinones bearing a pyrrole Mannich base moiety as angiokinase inhibitors.

Qin M, Yan S, Wang L, Zhang H, Tian Y, Zhao Y, Gong P. Qin M, et al. Among authors: tian y. Bioorg Med Chem. 2017 Mar 15;25(6):1778-1786. doi: 10.1016/j.bmc.2017.01.039. Epub 2017 Jan 25. Bioorg Med Chem. 2017. PMID: 28190652

8

Novel methyl indolinone-6-carboxylates containing an indole moiety as angiokinase inhibitors.

Qin M, Tian Y, Sun X, Yu S, Xia J, Gong P, Zhang H, Zhao Y. Qin M, et al. Among authors: tian y. Eur J Med Chem. 2017 Oct 20;139:492-502. doi: 10.1016/j.ejmech.2017.08.031. Epub 2017 Aug 14. Eur J Med Chem. 2017. PMID: 28826084

9

Design, synthesis and biological evaluation of thieno[3,2-d]pyrimidine derivatives containing aroyl hydrazone or aryl hydrazide moieties for PI3K and mTOR dual inhibition.

Han Y, Tian Y, Wang R, Fu S, Jiang J, Dong J, Qin M, Hou Y, Zhao Y. Han Y, et al. Among authors: tian y. Bioorg Chem. 2020 Nov;104:104197. doi: 10.1016/j.bioorg.2020.104197. Epub 2020 Aug 28. Bioorg Chem. 2020. PMID: 32927132

10

Synthesis and biological evaluation of new series of benzamide derivatives containing urea moiety as sEH inhibitors.

Tian Y, Li S, Yang P, Su X, Liu J, Lv X, Dong K, Yang T, Duan M, Hu G, Yue H, Sun Y, Sun Y, Zhang H, Du Z, Miao Z, Tong M, Hou Y, Gao Z, Zhao Y. Tian Y, et al. Bioorg Med Chem Lett. 2022 Aug 15;70:128805. doi: 10.1016/j.bmcl.2022.128805. Epub 2022 May 19. Bioorg Med Chem Lett. 2022. PMID: 35598794

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