Zhang H - Search Results

1

Structural modifications of indolinones bearing a pyrrole moiety and discovery of a multi-kinase inhibitor with potent antitumor activity.

Qin M, Tian Y, Han X, Cao Q, Zheng S, Liu C, Wu X, Liu L, Meng Y, Wang X, Zhang H, Hou Y. Qin M, et al. Among authors: zhang h. Bioorg Med Chem. 2020 Jun 1;28(11):115486. doi: 10.1016/j.bmc.2020.115486. Epub 2020 Apr 3. Bioorg Med Chem. 2020. PMID: 32305182

2

SOMG-833, a novel selective c-MET inhibitor, blocks c-MET-dependent neoplastic effects and exerts antitumor activity.

Zhang HT, Wang L, Ai J, Chen Y, He CX, Ji YC, Huang M, Yang JY, Zhang A, Ding J, Geng MY. Zhang HT, et al. J Pharmacol Exp Ther. 2014 Jul;350(1):36-45. doi: 10.1124/jpet.114.214817. Epub 2014 Apr 16. J Pharmacol Exp Ther. 2014. PMID: 24741075

3

Discovery of novel diaryl urea derivatives bearing a triazole moiety as potential antitumor agents.

Qin M, Yan S, Wang L, Zhang H, Zhao Y, Wu S, Wu D, Gong P. Qin M, et al. Among authors: zhang h. Eur J Med Chem. 2016 Jun 10;115:1-13. doi: 10.1016/j.ejmech.2016.02.071. Epub 2016 Mar 3. Eur J Med Chem. 2016. PMID: 26991938

4

Novel 6-methoxycarbonyl indolinones bearing a pyrrole Mannich base moiety as angiokinase inhibitors.

Qin M, Yan S, Wang L, Zhang H, Tian Y, Zhao Y, Gong P. Qin M, et al. Among authors: zhang h. Bioorg Med Chem. 2017 Mar 15;25(6):1778-1786. doi: 10.1016/j.bmc.2017.01.039. Epub 2017 Jan 25. Bioorg Med Chem. 2017. PMID: 28190652

5

Novel methyl indolinone-6-carboxylates containing an indole moiety as angiokinase inhibitors.

Qin M, Tian Y, Sun X, Yu S, Xia J, Gong P, Zhang H, Zhao Y. Qin M, et al. Among authors: zhang h. Eur J Med Chem. 2017 Oct 20;139:492-502. doi: 10.1016/j.ejmech.2017.08.031. Epub 2017 Aug 14. Eur J Med Chem. 2017. PMID: 28826084

6

Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

Qin M, Cao Q, Zheng S, Tian Y, Zhang H, Xie J, Xie H, Liu Y, Zhao Y, Gong P. Qin M, et al. Among authors: zhang h. J Med Chem. 2019 May 9;62(9):4703-4715. doi: 10.1021/acs.jmedchem.9b00312. Epub 2019 Apr 19. J Med Chem. 2019. PMID: 30964291

7

Discovery of the programmed cell death-1/programmed cell death-ligand 1 interaction inhibitors bearing an indoline scaffold.

Qin M, Cao Q, Wu X, Liu C, Zheng S, Xie H, Tian Y, Xie J, Zhao Y, Hou Y, Zhang X, Xu B, Zhang H, Wang X. Qin M, et al. Among authors: zhang x, zhang h. Eur J Med Chem. 2020 Jan 15;186:111856. doi: 10.1016/j.ejmech.2019.111856. Epub 2019 Nov 9. Eur J Med Chem. 2020. PMID: 31734021

8

Insights into non-peptide small-molecule inhibitors of the PD-1/PD-L1 interaction: Development and perspective.

Wu X, Meng Y, Liu L, Gong G, Zhang H, Hou Y, Liu C, Wu D, Qin M. Wu X, et al. Among authors: zhang h. Bioorg Med Chem. 2021 Mar 1;33:116038. doi: 10.1016/j.bmc.2021.116038. Epub 2021 Jan 22. Bioorg Med Chem. 2021. PMID: 33517226 Review.

9

Discovery of 4-Arylindolines Containing a Thiazole Moiety as Potential Antitumor Agents Inhibiting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

Qin M, Meng Y, Yang H, Liu L, Zhang H, Wang S, Liu C, Wu X, Wu D, Tian Y, Hou Y, Zhao Y, Liu Y, Xu C, Wang L. Qin M, et al. Among authors: zhang h. J Med Chem. 2021 May 13;64(9):5519-5534. doi: 10.1021/acs.jmedchem.0c01958. Epub 2021 May 3. J Med Chem. 2021. PMID: 33938739

10

Yhhu3813 is a novel selective inhibitor of c-Met kinase that inhibits c-Met-dependent neoplastic phenotypes of human cancer cells.

He CX, Ai J, Xing WQ, Chen Y, Zhang HT, Huang M, Hu YH, Ding J, Geng MY. He CX, et al. Acta Pharmacol Sin. 2014 Jan;35(1):89-97. doi: 10.1038/aps.2013.125. Epub 2013 Nov 18. Acta Pharmacol Sin. 2014. PMID: 24241352 Free PMC article.

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