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An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup.
Gower M, Li X, Aguilar-Navarro AG, Lin B, Fernandez M, Edun G, Nader M, Rondeau V, Arruda A, Tierens A, Eames Seffernick A, Pölönen P, Durocher J, Wagenblast E, Yang L, Lee HS, Mullighan CG, Teachey D, Rashkovan M, Tremblay CS, Herranz D, Itkin T, Loghavi S, Dick JE, Schwartz G, Perusini MA, Sibai H, Hitzler J, Gruber TA, Minden M, Jones CL, Dolgalev I, Jahangiri S, Tikhonova AN. Gower M, et al. Among authors: jones cl. Sci Transl Med. 2025 Jan;17(779):eadr2012. doi: 10.1126/scitranslmed.adr2012. Epub 2025 Jan 1. Sci Transl Med. 2025. PMID: 39742502
Cysteamine dioxygenase (ADO) governs cancer cell mitochondrial redox homeostasis through proline metabolism.
Lee SCS, Pyo AHA, Mohammadi H, Zhang J, Dvorkin-Gheva A, Malbeteau L, Chung S, Khan S, Ciudad MT, Rondeau V, Cairns RA, Kislinger T, McGaha TL, Wouters BG, Reisz JA, Culp-Hill R, D'Alessandro A, Jones CL, Koritzinsky M. Lee SCS, et al. Among authors: jones cl. Sci Adv. 2024 Oct 4;10(40):eadq0355. doi: 10.1126/sciadv.adq0355. Epub 2024 Oct 2. Sci Adv. 2024. PMID: 39356760 Free PMC article.
Efficacy and safety of GLP-1 analog ecnoglutide in adults with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 2 trial.
Zhu D, Wang W, Tong G, Ma G, Ma J, Han J, Zhang X, Liu Y, Gan S, Qin H, Zheng Q, Ning J, Zhu Z, Guo M, Bu Y, Li Y, Jones CL, Fenaux M, Junaidi MK, Xu S, Pan H. Zhu D, et al. Among authors: jones cl. Nat Commun. 2024 Sep 27;15(1):8408. doi: 10.1038/s41467-024-52353-y. Nat Commun. 2024. PMID: 39333121 Free PMC article. Clinical Trial.
340 results