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The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan.
Keating ST, Groh L, van der Heijden CDCC, Rodriguez H, Dos Santos JC, Fanucchi S, Okabe J, Kaipananickal H, van Puffelen JH, Helder L, Noz MP, Matzaraki V, Li Y, de Bree LCJ, Koeken VACM, Moorlag SJCFM, Mourits VP, Domínguez-Andrés J, Oosting M, Bulthuis EP, Koopman WJH, Mhlanga M, El-Osta A, Joosten LAB, Netea MG, Riksen NP. Keating ST, et al. Cell Rep. 2020 Apr 21;31(3):107548. doi: 10.1016/j.celrep.2020.107548. Cell Rep. 2020. PMID: 32320649 Free PMC article.
Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis.
Domínguez-Andrés J, Arts RJW, Ter Horst R, Gresnigt MS, Smeekens SP, Ratter JM, Lachmandas E, Boutens L, van de Veerdonk FL, Joosten LAB, Notebaart RA, Ardavín C, Netea MG. Domínguez-Andrés J, et al. PLoS Pathog. 2017 Sep 18;13(9):e1006632. doi: 10.1371/journal.ppat.1006632. eCollection 2017 Sep. PLoS Pathog. 2017. PMID: 28922415 Free PMC article.
Long-term reprogramming of the innate immune system.
Dominguez-Andres J, Netea MG. Dominguez-Andres J, et al. J Leukoc Biol. 2019 Feb;105(2):329-338. doi: 10.1002/JLB.MR0318-104R. Epub 2018 Jul 12. J Leukoc Biol. 2019. PMID: 29999546 Review.
The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.
Domínguez-Andrés J, Novakovic B, Li Y, Scicluna BP, Gresnigt MS, Arts RJW, Oosting M, Moorlag SJCFM, Groh LA, Zwaag J, Koch RM, Ter Horst R, Joosten LAB, Wijmenga C, Michelucci A, van der Poll T, Kox M, Pickkers P, Kumar V, Stunnenberg H, Netea MG. Domínguez-Andrés J, et al. Cell Metab. 2019 Jan 8;29(1):211-220.e5. doi: 10.1016/j.cmet.2018.09.003. Epub 2018 Oct 4. Cell Metab. 2019. PMID: 30293776 Free article.
Itaconate as an immune modulator.
Ferreira AV, Netea MG, Domínguez-Andrés J. Ferreira AV, et al. Aging (Albany NY). 2019 Jun 24;11(12):3898-3899. doi: 10.18632/aging.102057. Aging (Albany NY). 2019. PMID: 31235675 Free PMC article. No abstract available.
Advances in understanding molecular regulation of innate immune memory.
Domínguez-Andrés J, Fanucchi S, Joosten LAB, Mhlanga MM, Netea MG. Domínguez-Andrés J, et al. Curr Opin Cell Biol. 2020 Apr;63:68-75. doi: 10.1016/j.ceb.2019.12.006. Epub 2020 Jan 25. Curr Opin Cell Biol. 2020. PMID: 31991317 Free article. Review.
77 results