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Page 1
Excessive EP4 Signaling in Smooth Muscle Cells Induces Abdominal Aortic Aneurysm by Amplifying Inflammation.
Hiromi T, Yokoyama U, Kurotaki D, Mamun A, Ishiwata R, Ichikawa Y, Nishihara H, Umemura M, Fujita T, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Takeuchi I, Masuda M, Breyer RM, Tamura T, Ishikawa Y. Hiromi T, et al. Among authors: breyer rm. Arterioscler Thromb Vasc Biol. 2020 Jun;40(6):1559-1573. doi: 10.1161/ATVBAHA.120.314297. Epub 2020 Apr 23. Arterioscler Thromb Vasc Biol. 2020. PMID: 32321307 Free PMC article.
Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE2 (Prostaglandin E2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury.
Hao H, Hu S, Wan Q, Xu C, Chen H, Zhu L, Xu Z, Meng J, Breyer RM, Li N, Liu DP, FitzGerald GA, Wang M. Hao H, et al. Among authors: breyer rm. Arterioscler Thromb Vasc Biol. 2018 May;38(5):1115-1124. doi: 10.1161/ATVBAHA.118.310713. Epub 2018 Mar 29. Arterioscler Thromb Vasc Biol. 2018. PMID: 29599139 Free PMC article.
Inactivation of the E-prostanoid 3 receptor attenuates the angiotensin II pressor response via decreasing arterial contractility.
Chen L, Miao Y, Zhang Y, Dou D, Liu L, Tian X, Yang G, Pu D, Zhang X, Kang J, Gao Y, Wang S, Breyer MD, Wang N, Zhu Y, Huang Y, Breyer RM, Guan Y. Chen L, et al. Among authors: breyer rm, breyer md. Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):3024-32. doi: 10.1161/ATVBAHA.112.254052. Epub 2012 Oct 11. Arterioscler Thromb Vasc Biol. 2012. PMID: 23065824 Free PMC article.
Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis.
Duffin R, O'Connor RA, Crittenden S, Forster T, Yu C, Zheng X, Smyth D, Robb CT, Rossi F, Skouras C, Tang S, Richards J, Pellicoro A, Weller RB, Breyer RM, Mole DJ, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Ghazal P, Howie SE, Rossi AG, Yao C. Duffin R, et al. Among authors: breyer rm. Science. 2016 Mar 18;351(6279):1333-8. doi: 10.1126/science.aad9903. Science. 2016. PMID: 26989254 Free PMC article.
Epithelial EP4 plays an essential role in maintaining homeostasis in colon.
Matsumoto Y, Nakanishi Y, Yoshioka T, Yamaga Y, Masuda T, Fukunaga Y, Sono M, Yoshikawa T, Nagao M, Araki O, Ogawa S, Goto N, Hiramatsu Y, Breyer RM, Fukuda A, Seno H. Matsumoto Y, et al. Among authors: breyer rm. Sci Rep. 2019 Oct 23;9(1):15244. doi: 10.1038/s41598-019-51639-2. Sci Rep. 2019. PMID: 31645712 Free PMC article.
135 results