Tam AJ - Search Results

1

Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells.

Oh MH, Sun IH, Zhao L, Leone RD, Sun IM, Xu W, Collins SL, Tam AJ, Blosser RL, Patel CH, Englert JM, Arwood ML, Wen J, Chan-Li Y, Tenora L, Majer P, Rais R, Slusher BS, Horton MR, Powell JD. Oh MH, et al. Among authors: tam aj. J Clin Invest. 2020 Jul 1;130(7):3865-3884. doi: 10.1172/JCI131859. J Clin Invest. 2020. PMID: 32324593 Free PMC article.

2

STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients.

Vasquez-Dunddel D, Pan F, Zeng Q, Gorbounov M, Albesiano E, Fu J, Blosser RL, Tam AJ, Bruno T, Zhang H, Pardoll D, Kim Y. Vasquez-Dunddel D, et al. Among authors: tam aj. J Clin Invest. 2013 Apr;123(4):1580-9. doi: 10.1172/JCI60083. J Clin Invest. 2013. PMID: 23454751 Free PMC article.

3

Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells.

Kim K, Skora AD, Li Z, Liu Q, Tam AJ, Blosser RL, Diaz LA Jr, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Kim K, et al. Among authors: tam aj. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11774-9. doi: 10.1073/pnas.1410626111. Epub 2014 Jul 28. Proc Natl Acad Sci U S A. 2014. PMID: 25071169 Free PMC article.

4

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints.

Llosa NJ, Cruise M, Tam A, Wicks EC, Hechenbleikner EM, Taube JM, Blosser RL, Fan H, Wang H, Luber BS, Zhang M, Papadopoulos N, Kinzler KW, Vogelstein B, Sears CL, Anders RA, Pardoll DM, Housseau F. Llosa NJ, et al. Cancer Discov. 2015 Jan;5(1):43-51. doi: 10.1158/2159-8290.CD-14-0863. Epub 2014 Oct 30. Cancer Discov. 2015. PMID: 25358689 Free PMC article.

5

Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes.

Skora AD, Douglass J, Hwang MS, Tam AJ, Blosser RL, Gabelli SB, Cao J, Diaz LA Jr, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Skora AD, et al. Among authors: tam aj. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9967-72. doi: 10.1073/pnas.1511996112. Epub 2015 Jul 27. Proc Natl Acad Sci U S A. 2015. PMID: 26216968 Free PMC article.

6

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation.

Pollizzi KN, Sun IH, Patel CH, Lo YC, Oh MH, Waickman AT, Tam AJ, Blosser RL, Wen J, Delgoffe GM, Powell JD. Pollizzi KN, et al. Among authors: tam aj. Nat Immunol. 2016 Jun;17(6):704-11. doi: 10.1038/ni.3438. Epub 2016 Apr 11. Nat Immunol. 2016. PMID: 27064374 Free PMC article.

7

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells.

Sadtler K, Estrellas K, Allen BW, Wolf MT, Fan H, Tam AJ, Patel CH, Luber BS, Wang H, Wagner KR, Powell JD, Housseau F, Pardoll DM, Elisseeff JH. Sadtler K, et al. Among authors: tam aj. Science. 2016 Apr 15;352(6283):366-70. doi: 10.1126/science.aad9272. Science. 2016. PMID: 27081073 Free PMC article.

8

The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis.

Thiele Orberg E, Fan H, Tam AJ, Dejea CM, Destefano Shields CE, Wu S, Chung L, Finard BB, Wu X, Fathi P, Ganguly S, Fu J, Pardoll DM, Sears CL, Housseau F. Thiele Orberg E, et al. Among authors: tam aj. Mucosal Immunol. 2017 Mar;10(2):421-433. doi: 10.1038/mi.2016.53. Epub 2016 Jun 15. Mucosal Immunol. 2017. PMID: 27301879 Free PMC article.

9

mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages.

Oh MH, Collins SL, Sun IH, Tam AJ, Patel CH, Arwood ML, Chan-Li Y, Powell JD, Horton MR. Oh MH, et al. Among authors: tam aj. Cell Rep. 2017 Sep 5;20(10):2439-2454. doi: 10.1016/j.celrep.2017.08.046. Cell Rep. 2017. PMID: 28877476 Free PMC article.

10

Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment.

Muroyama Y, Nirschl TR, Kochel CM, Lopez-Bujanda Z, Theodros D, Mao W, Carrera-Haro MA, Ghasemzadeh A, Marciscano AE, Velarde E, Tam AJ, Thoburn CJ, Uddin M, Meeker AK, Anders RA, Pardoll DM, Drake CG. Muroyama Y, et al. Among authors: tam aj. Cancer Immunol Res. 2017 Nov;5(11):992-1004. doi: 10.1158/2326-6066.CIR-17-0040. Epub 2017 Oct 2. Cancer Immunol Res. 2017. PMID: 28970196 Free PMC article.

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