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Page 1
An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs).
Avila AM, Bebenek I, Bonzo JA, Bourcier T, Davis Bruno KL, Carlson DB, Dubinion J, Elayan I, Harrouk W, Lee SL, Mendrick DL, Merrill JC, Peretz J, Place E, Saulnier M, Wange RL, Yao J, Zhao D, Brown PC. Avila AM, et al. Among authors: harrouk w. Regul Toxicol Pharmacol. 2020 Jul;114:104662. doi: 10.1016/j.yrtph.2020.104662. Epub 2020 Apr 20. Regul Toxicol Pharmacol. 2020. PMID: 32325112
Micro-CT imaging: Developing criteria for examining fetal skeletons in regulatory developmental toxicology studies - A workshop report.
Solomon HM, Makris SL, Alsaid H, Bermudez O, Beyer BK, Chen A, Chen CL, Chen Z, Chmielewski G, DeLise AM, de Schaepdrijver L, Dogdas B, French J, Harrouk W, Helfgott J, Henkelman RM, Hesterman J, Hew KW, Hoberman A, Lo CW, McDougal A, Minck DR, Scott L, Stewart J, Sutherland V, Tatiparthi AK, Winkelmann CT, Wise LD, Wood SL, Ying X. Solomon HM, et al. Among authors: harrouk w. Regul Toxicol Pharmacol. 2016 Jun;77:100-8. doi: 10.1016/j.yrtph.2016.02.018. Epub 2016 Feb 27. Regul Toxicol Pharmacol. 2016. PMID: 26930635 Free article.
Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects.
Theunissen PT, Beken S, Beyer B, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, de Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Y Hui J, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH. Theunissen PT, et al. Among authors: harrouk w. Crit Rev Toxicol. 2017 May;47(5):402-414. doi: 10.1080/10408444.2016.1224808. Epub 2016 Oct 21. Crit Rev Toxicol. 2017. PMID: 27766926 Free article.
Nonclinical aspects of venous thrombosis in pregnancy.
Struble E, Harrouk W, DeFelice A, Tesfamariam B. Struble E, et al. Among authors: harrouk w. Birth Defects Res C Embryo Today. 2015 Sep;105(3):190-200. doi: 10.1002/bdrc.21111. Epub 2015 Sep 25. Birth Defects Res C Embryo Today. 2015. PMID: 26404176 Free PMC article. Review.
Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects.
Theunissen PT, Beken S, Beyer BK, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, De Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Hui JY, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH. Theunissen PT, et al. Among authors: harrouk w. Crit Rev Toxicol. 2016 Nov;46(10):900-910. doi: 10.1080/10408444.2016.1224807. Epub 2016 Oct 19. Crit Rev Toxicol. 2016. PMID: 27848393 Free PMC article. Review.
ILSI/HESI maternal toxicity workshop summary: maternal toxicity and its impact on study design and data interpretation.
Beyer BK, Chernoff N, Danielsson BR, Davis-Bruno K, Harrouk W, Hood RD, Janer G, Liminga UW, Kim JH, Rocca M, Rogers J, Scialli AR. Beyer BK, et al. Among authors: harrouk w. Birth Defects Res B Dev Reprod Toxicol. 2011 Feb;92(1):36-51. doi: 10.1002/bdrb.20281. Epub 2010 Dec 23. Birth Defects Res B Dev Reprod Toxicol. 2011. PMID: 21312321
26 results