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Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z. Zhang L, et al. Among authors: zhao y, zhao w. Science. 2020 Jun 12;368(6496):1211-1219. doi: 10.1126/science.aba9102. Epub 2020 Apr 23. Science. 2020. PMID: 32327601
Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target.
Zhang B, Li J, Yang X, Wu L, Zhang J, Yang Y, Zhao Y, Zhang L, Yang X, Yang X, Cheng X, Liu Z, Jiang B, Jiang H, Guddat LW, Yang H, Rao Z. Zhang B, et al. Among authors: zhao y. Cell. 2019 Jan 24;176(3):636-648.e13. doi: 10.1016/j.cell.2019.01.003. Cell. 2019. PMID: 30682372 Free article.
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors.
Jin Z, Du X, Xu Y, Deng Y, Liu M, Zhao Y, Zhang B, Li X, Zhang L, Peng C, Duan Y, Yu J, Wang L, Yang K, Liu F, Jiang R, Yang X, You T, Liu X, Yang X, Bai F, Liu H, Liu X, Guddat LW, Xu W, Xiao G, Qin C, Shi Z, Jiang H, Rao Z, Yang H. Jin Z, et al. Among authors: zhao y. Nature. 2020 Jun;582(7811):289-293. doi: 10.1038/s41586-020-2223-y. Epub 2020 Apr 9. Nature. 2020. PMID: 32272481
Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Gao Y, Yan L, Huang Y, Liu F, Zhao Y, Cao L, Wang T, Sun Q, Ming Z, Zhang L, Ge J, Zheng L, Zhang Y, Wang H, Zhu Y, Zhu C, Hu T, Hua T, Zhang B, Yang X, Li J, Yang H, Liu Z, Xu W, Guddat LW, Wang Q, Lou Z, Rao Z. Gao Y, et al. Among authors: zhao y. Science. 2020 May 15;368(6492):779-782. doi: 10.1126/science.abb7498. Epub 2020 Apr 10. Science. 2020. PMID: 32277040 Free PMC article.
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Dai W, Zhang B, Jiang XM, Su H, Li J, Zhao Y, Xie X, Jin Z, Peng J, Liu F, Li C, Li Y, Bai F, Wang H, Cheng X, Cen X, Hu S, Yang X, Wang J, Liu X, Xiao G, Jiang H, Rao Z, Zhang LK, Xu Y, Yang H, Liu H. Dai W, et al. Among authors: zhao y. Science. 2020 Jun 19;368(6497):1331-1335. doi: 10.1126/science.abb4489. Epub 2020 Apr 22. Science. 2020. PMID: 32321856 Free PMC article.
Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2.
Zhang L, Zhao Y, Gao R, Li J, Yang X, Gao Y, Zhao W, Gurcha SS, Veerapen N, Batt SM, Besra KK, Xu W, Bi L, Zhang X, Guddat LW, Yang H, Wang Q, Besra GS, Rao Z. Zhang L, et al. Among authors: zhao y, zhao w. Protein Cell. 2020 Jul;11(7):505-517. doi: 10.1007/s13238-020-00726-6. Epub 2020 May 3. Protein Cell. 2020. PMID: 32363534 Free PMC article.
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors.
Zhao Y, Du X, Duan Y, Pan X, Sun Y, You T, Han L, Jin Z, Shang W, Yu J, Guo H, Liu Q, Wu Y, Peng C, Wang J, Zhu C, Yang X, Yang K, Lei Y, Guddat LW, Xu W, Xiao G, Sun L, Zhang L, Rao Z, Yang H. Zhao Y, et al. Protein Cell. 2021 Nov;12(11):877-888. doi: 10.1007/s13238-021-00836-9. Epub 2021 Apr 17. Protein Cell. 2021. PMID: 33864621 Free PMC article.
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