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Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes.
Mizuno-Iijima S, Ayabe S, Kato K, Matoba S, Ikeda Y, Dinh TTH, Le HT, Suzuki H, Nakashima K, Hasegawa Y, Hamada Y, Tanimoto Y, Daitoku Y, Iki N, Ishida M, Ibrahim EAE, Nakashiba T, Hamada M, Murata K, Miwa Y, Okada-Iwabu M, Iwabu M, Yagami KI, Ogura A, Obata Y, Takahashi S, Mizuno S, Yoshiki A, Sugiyama F. Mizuno-Iijima S, et al. Among authors: hamada m, hamada y. Methods. 2021 Jul;191:23-31. doi: 10.1016/j.ymeth.2020.04.007. Epub 2020 Apr 22. Methods. 2021. PMID: 32334080 Free article.
DAJIN enables multiplex genotyping to simultaneously validate intended and unintended target genome editing outcomes.
Kuno A, Ikeda Y, Ayabe S, Kato K, Sakamoto K, Suzuki SR, Morimoto K, Wakimoto A, Mikami N, Ishida M, Iki N, Hamada Y, Takemura M, Daitoku Y, Tanimoto Y, Dinh TTH, Murata K, Hamada M, Muratani M, Yoshiki A, Sugiyama F, Takahashi S, Mizuno S. Kuno A, et al. Among authors: hamada m, hamada y. PLoS Biol. 2022 Jan 18;20(1):e3001507. doi: 10.1371/journal.pbio.3001507. eCollection 2022 Jan. PLoS Biol. 2022. PMID: 35041655 Free PMC article.
Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway.
Dinh TTH, Iseki H, Mizuno S, Iijima-Mizuno S, Tanimoto Y, Daitoku Y, Kato K, Hamada Y, Hasan ASH, Suzuki H, Murata K, Muratani M, Ema M, Kim JD, Ishida J, Fukamizu A, Kato M, Takahashi S, Yagami KI, Wilson V, Arkell RM, Sugiyama F. Dinh TTH, et al. Among authors: hamada y. Elife. 2021 May 5;10:e50346. doi: 10.7554/eLife.50346. Elife. 2021. PMID: 33949947 Free PMC article.
CD44v, S1PR1, HER3, MET and cancer-associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb.
Nakano T, Okita K, Okazaki S, Yoshimoto S, Masuko S, Yagi H, Kato K, Tomioka Y, Imai K, Hamada Y, Masuko K, Shimada-Takaura K, Nagai N, Saya H, Arai T, Ishiwata T, Masuko T. Nakano T, et al. Among authors: hamada y. FEBS Open Bio. 2025 Jan 5. doi: 10.1002/2211-5463.13963. Online ahead of print. FEBS Open Bio. 2025. PMID: 39757718 Free article.
2,082 results