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Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes.
Mizuno-Iijima S, Ayabe S, Kato K, Matoba S, Ikeda Y, Dinh TTH, Le HT, Suzuki H, Nakashima K, Hasegawa Y, Hamada Y, Tanimoto Y, Daitoku Y, Iki N, Ishida M, Ibrahim EAE, Nakashiba T, Hamada M, Murata K, Miwa Y, Okada-Iwabu M, Iwabu M, Yagami KI, Ogura A, Obata Y, Takahashi S, Mizuno S, Yoshiki A, Sugiyama F. Mizuno-Iijima S, et al. Among authors: le ht. Methods. 2021 Jul;191:23-31. doi: 10.1016/j.ymeth.2020.04.007. Epub 2020 Apr 22. Methods. 2021. PMID: 32334080 Free article.
EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice.
Osawa Y, Murata K, Usui M, Kuba Y, Le HT, Mikami N, Nakagawa T, Daitoku Y, Kato K, Shawki HH, Ikeda Y, Kuno A, Morimoto K, Tanimoto Y, Dinh TTH, Yagami KI, Ema M, Yoshida S, Takahashi S, Mizuno S, Sugiyama F. Osawa Y, et al. Among authors: le ht. Elife. 2021 May 11;10:e59759. doi: 10.7554/eLife.59759. Elife. 2021. PMID: 33973520 Free PMC article.
Exocyst complex component 1 (Exoc1) loss in dormant oocyte disrupts c-KIT and growth differentiation factor (GDF9) subcellular localization and causes female infertility in mice.
Nguyen CLK, Kuba Y, Le HT, Shawki HH, Mikami N, Aoki M, Yasuhara N, Suzuki H, Mizuno-Iijima S, Ayabe S, Osawa Y, Fujiyama T, Dinh TTH, Ishida M, Daitoku Y, Tanimoto Y, Murata K, Kang W, Ema M, Hirao Y, Ogura A, Takahashi S, Sugiyama F, Mizuno S. Nguyen CLK, et al. Among authors: le ht. Cell Death Discov. 2025 Jan 20;11(1):17. doi: 10.1038/s41420-025-02291-5. Cell Death Discov. 2025. PMID: 39833146 Free PMC article.
573 results