Sibley DR - Search Results

1

Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D₃ Dopamine Receptor Agonist.

Moritz AE, Free RB, Weiner WS, Akano EO, Gandhi D, Abramyan A, Keck TM, Ferrer M, Hu X, Southall N, Steiner J, Aubé J, Shi L, Frankowski KJ, Sibley DR. Moritz AE, et al. Among authors: sibley dr. J Med Chem. 2020 May 28;63(10):5526-5567. doi: 10.1021/acs.jmedchem.0c00424. Epub 2020 May 12. J Med Chem. 2020. PMID: 32342685 Free PMC article.

2

Dopamine receptor agonist potencies for inhibition of cell firing correlate with dopamine D3 receptor binding affinities.

Kreiss DS, Bergstrom DA, Gonzalez AM, Huang KX, Sibley DR, Walters JR. Kreiss DS, et al. Among authors: sibley dr. Eur J Pharmacol. 1995 Apr 24;277(2-3):209-14. doi: 10.1016/0014-2999(95)00069-w. Eur J Pharmacol. 1995. PMID: 7493610

3

[3H]7-OH-DPAT is capable of labeling dopamine D2 as well as D3 receptors.

Gonzalez AM, Sibley DR. Gonzalez AM, et al. Among authors: sibley dr. Eur J Pharmacol. 1995 Jan 5;272(1):R1-3. doi: 10.1016/0014-2999(94)00738-s. Eur J Pharmacol. 1995. PMID: 7713138

4

Chimeric D2/D3 dopamine receptor coupling to adenylyl cyclase.

Lachowicz JE, Sibley DR. Lachowicz JE, et al. Among authors: sibley dr. Biochem Biophys Res Commun. 1997 Aug 18;237(2):394-9. doi: 10.1006/bbrc.1997.7146. Biochem Biophys Res Commun. 1997. PMID: 9268722

5

The role of phosphorylation/dephosphorylation in agonist-induced desensitization of D1 dopamine receptor function: evidence for a novel pathway for receptor dephosphorylation.

Gardner B, Liu ZF, Jiang D, Sibley DR. Gardner B, et al. Among authors: sibley dr. Mol Pharmacol. 2001 Feb;59(2):310-21. doi: 10.1124/mol.59.2.310. Mol Pharmacol. 2001. PMID: 11160868

6

The role of phosphorylation in D1 dopamine receptor desensitization: evidence for a novel mechanism of arrestin association.

Kim OJ, Gardner BR, Williams DB, Marinec PS, Cabrera DM, Peters JD, Mak CC, Kim KM, Sibley DR. Kim OJ, et al. Among authors: sibley dr. J Biol Chem. 2004 Feb 27;279(9):7999-8010. doi: 10.1074/jbc.M308281200. Epub 2003 Dec 4. J Biol Chem. 2004. PMID: 14660631 Free PMC article.

7

Protein kinase C mediates phosphorylation, desensitization, and trafficking of the D2 dopamine receptor.

Namkung Y, Sibley DR. Namkung Y, et al. Among authors: sibley dr. J Biol Chem. 2004 Nov 19;279(47):49533-41. doi: 10.1074/jbc.M408319200. Epub 2004 Sep 3. J Biol Chem. 2004. PMID: 15347675 Free article.

8

D1 and D2 dopamine receptor expression is regulated by direct interaction with the chaperone protein calnexin.

Free RB, Hazelwood LA, Cabrera DM, Spalding HN, Namkung Y, Rankin ML, Sibley DR. Free RB, et al. Among authors: sibley dr. J Biol Chem. 2007 Jul 20;282(29):21285-300. doi: 10.1074/jbc.M701555200. Epub 2007 Mar 29. J Biol Chem. 2007. PMID: 17395585 Free article.

9

Reciprocal modulation of function between the D1 and D2 dopamine receptors and the Na+,K+-ATPase.

Hazelwood LA, Free RB, Cabrera DM, Skinbjerg M, Sibley DR. Hazelwood LA, et al. Among authors: sibley dr. J Biol Chem. 2008 Dec 26;283(52):36441-53. doi: 10.1074/jbc.M805520200. Epub 2008 Nov 4. J Biol Chem. 2008. PMID: 18984584 Free PMC article.

10

Identifying novel protein-protein interactions using co-immunoprecipitation and mass spectroscopy.

Free RB, Hazelwood LA, Sibley DR. Free RB, et al. Among authors: sibley dr. Curr Protoc Neurosci. 2009 Jan;Chapter 5:Unit 5.28. doi: 10.1002/0471142301.ns0528s46. Curr Protoc Neurosci. 2009. PMID: 19170023 Free PMC article.

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