Porteus MH - Search Results

1

DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis.

Adair JE, Enstrom MR, Haworth KG, Schefter LE, Shahbazi R, Humphrys DR, Porter S, Tam K, Porteus MH, Kiem HP. Adair JE, et al. Among authors: porteus mh. Mol Ther Methods Clin Dev. 2020 Mar 30;17:796-809. doi: 10.1016/j.omtm.2020.03.021. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32355868 Free PMC article.

2

Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels.

Pruett-Miller SM, Reading DW, Porter SN, Porteus MH. Pruett-Miller SM, et al. Among authors: porteus mh. PLoS Genet. 2009 Feb;5(2):e1000376. doi: 10.1371/journal.pgen.1000376. Epub 2009 Feb 13. PLoS Genet. 2009. PMID: 19214211 Free PMC article.

3

Lentiviral and targeted cellular barcoding reveals ongoing clonal dynamics of cell lines in vitro and in vivo.

Porter SN, Baker LC, Mittelman D, Porteus MH. Porter SN, et al. Among authors: porteus mh. Genome Biol. 2014 May 30;15(5):R75. doi: 10.1186/gb-2014-15-5-r75. Genome Biol. 2014. PMID: 24886633 Free PMC article.

4

Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development.

Cannon P, Asokan A, Czechowicz A, Hammond P, Kohn DB, Lieber A, Malik P, Marks P, Porteus M, Verhoeyen E, Weissman D, Weissman I, Kiem HP. Cannon P, et al. Hum Gene Ther. 2021 Jan;32(1-2):31-42. doi: 10.1089/hum.2020.263. Hum Gene Ther. 2021. PMID: 33427035 Free PMC article.

5

Molecular dynamics of genome editing with CRISPR-Cas9 and rAAV6 virus in human HSPCs to treat sickle cell disease.

Xu L, Lahiri P, Skowronski J, Bhatia N, Lattanzi A, Porteus MH. Xu L, et al. Among authors: porteus mh. Mol Ther Methods Clin Dev. 2023 Jul 27;30:317-331. doi: 10.1016/j.omtm.2023.07.009. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37637384 Free PMC article.

6

Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs.

Ellis BL, Hirsch ML, Porter SN, Samulski RJ, Porteus MH. Ellis BL, et al. Among authors: porteus mh. Gene Ther. 2013 Jan;20(1):35-42. doi: 10.1038/gt.2011.211. Epub 2012 Jan 19. Gene Ther. 2013. PMID: 22257934 Free PMC article.

7

Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.

de Alencastro G, Puzzo F, Pavel-Dinu M, Zhang F, Pillay S, Majzoub K, Tiffany M, Jang H, Sheikali A, Cromer MK, Meetei R, Carette JE, Porteus MH, Pekrun K, Kay MA. de Alencastro G, et al. Among authors: porteus mh. Mol Ther. 2021 Mar 3;29(3):1016-1027. doi: 10.1016/j.ymthe.2020.10.020. Epub 2020 Oct 22. Mol Ther. 2021. PMID: 33678249 Free PMC article.

8

Clinically relevant gene editing in hematopoietic stem cells for the treatment of pyruvate kinase deficiency.

Fañanas-Baquero S, Quintana-Bustamante O, Dever DP, Alberquilla O, Sanchez-Dominguez R, Camarena J, Ojeda-Perez I, Dessy-Rodriguez M, Turk R, Schubert MS, Lattanzi A, Xu L, Lopez-Lorenzo JL, Bianchi P, Bueren JA, Behlke MA, Porteus M, Segovia JC. Fañanas-Baquero S, et al. Mol Ther Methods Clin Dev. 2021 May 14;22:237-248. doi: 10.1016/j.omtm.2021.05.001. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34485608 Free PMC article.

9

Generation of an HIV resistant T-cell line by targeted "stacking" of restriction factors.

Voit RA, McMahon MA, Sawyer SL, Porteus MH. Voit RA, et al. Among authors: porteus mh. Mol Ther. 2013 Apr;21(4):786-95. doi: 10.1038/mt.2012.284. Epub 2013 Jan 29. Mol Ther. 2013. PMID: 23358186 Free PMC article.

10

A crisper look at genome editing: RNA-guided genome modification.

Damian M, Porteus MH. Damian M, et al. Among authors: porteus mh. Mol Ther. 2013 Apr;21(4):720-2. doi: 10.1038/mt.2013.46. Mol Ther. 2013. PMID: 23542565 Free PMC article. No abstract available.

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