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Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing.
Chen JL, Zhang P, Abe M, Aikawa H, Zhang L, Frank AJ, Zembryski T, Hubbs C, Park H, Withka J, Steppan C, Rogers L, Cabral S, Pettersson M, Wager TT, Fountain MA, Rumbaugh G, Childs-Disney JL, Disney MD. Chen JL, et al. Among authors: rumbaugh g. J Am Chem Soc. 2020 May 13;142(19):8706-8727. doi: 10.1021/jacs.0c00768. Epub 2020 May 4. J Am Chem Soc. 2020. PMID: 32364710 Free PMC article.
Improved Scalability of Neuron-Based Phenotypic Screening Assays for Therapeutic Discovery in Neuropsychiatric Disorders.
Spicer TP, Hubbs C, Vaissiere T, Collia D, Rojas C, Kilinc M, Vick K, Madoux F, Baillargeon P, Shumate J, Martemyanov KA, Page DT, Puthanveettil S, Hodder P, Davis R, Miller CA, Scampavia L, Rumbaugh G. Spicer TP, et al. Among authors: rumbaugh g. Mol Neuropsychiatry. 2018 Feb;3(3):141-150. doi: 10.1159/000481731. Epub 2017 Nov 17. Mol Neuropsychiatry. 2018. PMID: 29594133 Free PMC article.
Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin II.
Radnai L, Surman M, Hafenbreidel M, Young EJ, Stremel RF, Lin L, Bdiri B, Pasetto P, Jin X, Geedy M, Partridge JR, Patel A, Conlon M, Sellers JR, Cameron MD, Rumbaugh G, Griffin PR, Kamenecka TM, Miller CA. Radnai L, et al. Among authors: rumbaugh g. ACS Chem Biol. 2021 Nov 19;16(11):2164-2173. doi: 10.1021/acschembio.1c00067. Epub 2021 Sep 24. ACS Chem Biol. 2021. PMID: 34558887
MicroRNA-182 regulates amygdala-dependent memory formation.
Griggs EM, Young EJ, Rumbaugh G, Miller CA. Griggs EM, et al. Among authors: rumbaugh g. J Neurosci. 2013 Jan 23;33(4):1734-40. doi: 10.1523/JNEUROSCI.2873-12.2013. J Neurosci. 2013. PMID: 23345246 Free PMC article.
89 results