Cuello LG - Search Results

1

The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels.

Coonen L, Mayeur E, De Neuter N, Snyders DJ, Cuello LG, Labro AJ. Coonen L, et al. Among authors: cuello lg. Biophys J. 2020 May 19;118(10):2612-2620. doi: 10.1016/j.bpj.2020.03.032. Epub 2020 Apr 15. Biophys J. 2020. PMID: 32365329 Free PMC article.

2

Molecular determinants of gating at the potassium-channel selectivity filter.

Cordero-Morales JF, Cuello LG, Zhao Y, Jogini V, Cortes DM, Roux B, Perozo E. Cordero-Morales JF, et al. Among authors: cuello lg. Nat Struct Mol Biol. 2006 Apr;13(4):311-8. doi: 10.1038/nsmb1069. Epub 2006 Mar 12. Nat Struct Mol Biol. 2006. PMID: 16532009

3

Hysteresis of KcsA potassium channel's activation- deactivation gating is caused by structural changes at the channel's selectivity filter.

Tilegenova C, Cortes DM, Cuello LG. Tilegenova C, et al. Among authors: cuello lg. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3234-3239. doi: 10.1073/pnas.1618101114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265056 Free PMC article.

4

Inverted allosteric coupling between activation and inactivation gates in K⁺ channels.

Labro AJ, Cortes DM, Tilegenova C, Cuello LG. Labro AJ, et al. Among authors: cuello lg. Proc Natl Acad Sci U S A. 2018 May 22;115(21):5426-5431. doi: 10.1073/pnas.1800559115. Epub 2018 May 7. Proc Natl Acad Sci U S A. 2018. PMID: 29735651 Free PMC article.

5

Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel.

Li J, Ostmeyer J, Cuello LG, Perozo E, Roux B. Li J, et al. Among authors: cuello lg. J Gen Physiol. 2018 Oct 1;150(10):1408-1420. doi: 10.1085/jgp.201812082. Epub 2018 Aug 2. J Gen Physiol. 2018. PMID: 30072373 Free PMC article.

6

Structure, function, and ion-binding properties of a K⁺ channel stabilized in the 2,4-ion-bound configuration.

Tilegenova C, Cortes DM, Jahovic N, Hardy E, Hariharan P, Guan L, Cuello LG. Tilegenova C, et al. Among authors: cuello lg. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16829-16834. doi: 10.1073/pnas.1901888116. Epub 2019 Aug 6. Proc Natl Acad Sci U S A. 2019. PMID: 31387976 Free PMC article.

7

TOK channels use the two gates in classical K⁺ channels to achieve outward rectification.

Lewis A, McCrossan ZA, Manville RW, Popa MO, Cuello LG, Goldstein SAN. Lewis A, et al. Among authors: cuello lg. FASEB J. 2020 Jul;34(7):8902-8919. doi: 10.1096/fj.202000545R. Epub 2020 Jun 10. FASEB J. 2020. PMID: 32519783 Free PMC article.

8

The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels.

Coonen L, Martinez-Morales E, Van De Sande DV, Snyders DJ, Cortes DM, Cuello LG, Labro AJ. Coonen L, et al. Among authors: cuello lg. Sci Adv. 2022 Sep 16;8(37):eabn1731. doi: 10.1126/sciadv.abn1731. Epub 2022 Sep 16. Sci Adv. 2022. PMID: 36112676 Free PMC article.

9

Voltage-dependent gating at the KcsA selectivity filter.

Cordero-Morales JF, Cuello LG, Perozo E. Cordero-Morales JF, et al. Among authors: cuello lg. Nat Struct Mol Biol. 2006 Apr;13(4):319-22. doi: 10.1038/nsmb1070. Epub 2006 Mar 12. Nat Struct Mol Biol. 2006. PMID: 16532008

10

Structural mechanism of C-type inactivation in K(+) channels.

Cuello LG, Jogini V, Cortes DM, Perozo E. Cuello LG, et al. Nature. 2010 Jul 8;466(7303):203-8. doi: 10.1038/nature09153. Nature. 2010. PMID: 20613835 Free PMC article.

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