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Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.
McEachin ZT, Gendron TF, Raj N, García-Murias M, Banerjee A, Purcell RH, Ward PJ, Todd TW, Merritt-Garza ME, Jansen-West K, Hales CM, García-Sobrino T, Quintáns B, Holler CJ, Taylor G, San Millán B, Teijeira S, Yamashita T, Ohkubo R, Boulis NM, Xu C, Wen Z, Streichenberger N; Neuro–CEB Neuropathology Network; Fogel BL, Kukar T, Abe K, Dickson DW, Arias M, Glass JD, Jiang J, Tansey MG, Sobrido MJ, Petrucelli L, Rossoll W, Bassell GJ. McEachin ZT, et al. Among authors: xu c. Neuron. 2020 Jul 22;107(2):292-305.e6. doi: 10.1016/j.neuron.2020.04.011. Epub 2020 May 5. Neuron. 2020. PMID: 32375063 Free PMC article.
Targeting Hsc70-based autophagy to eliminate amyloid β oligomers.
Dou J, Su P, Xu C, Wen Z, Mao Z, Li W. Dou J, et al. Among authors: xu c. Biochem Biophys Res Commun. 2020 Apr 16;524(4):923-928. doi: 10.1016/j.bbrc.2020.02.016. Epub 2020 Feb 11. Biochem Biophys Res Commun. 2020. PMID: 32057360 Free PMC article.
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies.
Kang Y, Zhou Y, Li Y, Han Y, Xu J, Niu W, Li Z, Liu S, Feng H, Huang W, Duan R, Xu T, Raj N, Zhang F, Dou J, Xu C, Wu H, Bassell GJ, Warren ST, Allen EG, Jin P, Wen Z. Kang Y, et al. Among authors: xu c, xu t, xu j. Nat Neurosci. 2021 Oct;24(10):1377-1391. doi: 10.1038/s41593-021-00913-6. Epub 2021 Aug 19. Nat Neurosci. 2021. PMID: 34413513 Free PMC article.
Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus.
Gokhale A, Lee CE, Zlatic SA, Freeman AAH, Shearing N, Hartwig C, Ogunbona O, Bassell JL, Wynne ME, Werner E, Xu C, Wen Z, Duong D, Seyfried NT, Bearden CE, Oláh VJ, Rowan MJM, Glausier JR, Lewis DA, Faundez V. Gokhale A, et al. Among authors: xu c. J Neurosci. 2021 Aug 4;41(31):6596-6616. doi: 10.1523/JNEUROSCI.2197-20.2021. Epub 2021 Jul 14. J Neurosci. 2021. PMID: 34261699 Free PMC article.
Pharmacological rescue in patient iPSC and mouse models with a rare DISC1 mutation.
Kim NS, Wen Z, Liu J, Zhou Y, Guo Z, Xu C, Lin YT, Yoon KJ, Park J, Cho M, Kim M, Wang X, Yu H, Sakamuru S, Christian KM, Hsu KS, Xia M, Li W, Ross CA, Margolis RL, Lu XY, Song H, Ming GL. Kim NS, et al. Among authors: xu c. Nat Commun. 2021 Mar 3;12(1):1398. doi: 10.1038/s41467-021-21713-3. Nat Commun. 2021. PMID: 33658519 Free PMC article.
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