Saliba KJ - Search Results

1

Toward a Stable and Potent Coenzyme A-Targeting Antiplasmodial Agent: Structure-Activity Relationship Studies of N-Phenethyl-α-methyl-pantothenamide.

Spry C, Barnard L, Kok M, Powell AK, Mahesh D, Tjhin ET, Saliba KJ, Strauss E, de Villiers M. Spry C, et al. Among authors: saliba kj. ACS Infect Dis. 2020 Jul 10;6(7):1844-1854. doi: 10.1021/acsinfecdis.0c00075. Epub 2020 May 28. ACS Infect Dis. 2020. PMID: 32375471

2

Correction: Thiamine analogues as inhibitors of pyruvate dehydrogenase and discovery of a thiamine analogue with non-thiamine related antiplasmodial activity.

Chan AHY, Fathoni I, Ho TCS, Saliba KJ, Leeper FJ. Chan AHY, et al. Among authors: saliba kj. RSC Med Chem. 2022 Dec 14;14(1):190. doi: 10.1039/d2md90043b. eCollection 2023 Jan 25. RSC Med Chem. 2022. PMID: 36755638 Free PMC article.

3

A class of pantothenic acid analogs inhibits Plasmodium falciparum pantothenate kinase and represses the proliferation of malaria parasites.

Spry C, Chai CL, Kirk K, Saliba KJ. Spry C, et al. Among authors: saliba kj. Antimicrob Agents Chemother. 2005 Nov;49(11):4649-57. doi: 10.1128/AAC.49.11.4649-4657.2005. Antimicrob Agents Chemother. 2005. PMID: 16251308 Free PMC article.

4

Feedback inhibition of pantothenate kinase regulates pantothenol uptake by the malaria parasite.

Lehane AM, Marchetti RV, Spry C, van Schalkwyk DA, Teng R, Kirk K, Saliba KJ. Lehane AM, et al. Among authors: saliba kj. J Biol Chem. 2007 Aug 31;282(35):25395-405. doi: 10.1074/jbc.M704610200. Epub 2007 Jun 20. J Biol Chem. 2007. PMID: 17581817 Free article.

5

Coenzyme A biosynthesis: an antimicrobial drug target.

Spry C, Kirk K, Saliba KJ. Spry C, et al. Among authors: saliba kj. FEMS Microbiol Rev. 2008 Jan;32(1):56-106. doi: 10.1111/j.1574-6976.2007.00093.x. FEMS Microbiol Rev. 2008. PMID: 18173393 Free article. Review.

6

The human malaria parasite Plasmodium falciparum is not dependent on host coenzyme A biosynthesis.

Spry C, Saliba KJ. Spry C, et al. Among authors: saliba kj. J Biol Chem. 2009 Sep 11;284(37):24904-13. doi: 10.1074/jbc.M109.025312. Epub 2009 Jul 7. J Biol Chem. 2009. PMID: 19584050 Free PMC article.

7

Pantothenate utilization by Plasmodium as a target for antimalarial chemotherapy.

Spry C, van Schalkwyk DA, Strauss E, Saliba KJ. Spry C, et al. Among authors: saliba kj. Infect Disord Drug Targets. 2010 Jun;10(3):200-16. doi: 10.2174/187152610791163390. Infect Disord Drug Targets. 2010. PMID: 20334619 Review.

8

Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated.

Spry C, Macuamule C, Lin Z, Virga KG, Lee RE, Strauss E, Saliba KJ. Spry C, et al. Among authors: saliba kj. PLoS One. 2013;8(2):e54974. doi: 10.1371/journal.pone.0054974. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405100 Free PMC article.

9

Studies with the Plasmodium falciparum hexokinase reveal that PfHT limits the rate of glucose entry into glycolysis.

Tjhin ET, Staines HM, van Schalkwyk DA, Krishna S, Saliba KJ. Tjhin ET, et al. Among authors: saliba kj. FEBS Lett. 2013 Oct 1;587(19):3182-7. doi: 10.1016/j.febslet.2013.07.052. Epub 2013 Aug 13. FEBS Lett. 2013. PMID: 23954294 Free article.

10

A miniaturized assay for measuring small molecule phosphorylation in the presence of complex matrices.

Spry C, Saliba KJ, Strauss E. Spry C, et al. Among authors: saliba kj. Anal Biochem. 2014 Apr 15;451:76-8. doi: 10.1016/j.ab.2013.12.010. Epub 2013 Dec 12. Anal Biochem. 2014. PMID: 24333332

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