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Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC. Yamamoto K, et al. Among authors: kakiuchi m. Nature. 2020 May;581(7806):100-105. doi: 10.1038/s41586-020-2229-5. Epub 2020 Apr 22. Nature. 2020. PMID: 32376951 Free PMC article.
Aberrant Cadherin11 expression predicts distant metastasis of gastric cancer.
Mita H, Katoh H, Komura D, Kakiuchi M, Abe H, Rokutan H, Yagi K, Nomura S, Ushiku T, Seto Y, Ishikawa S. Mita H, et al. Among authors: kakiuchi m. Pathol Res Pract. 2023 Feb;242:154294. doi: 10.1016/j.prp.2022.154294. Epub 2022 Dec 28. Pathol Res Pract. 2023. PMID: 36610328 Free article.
Bone marrow niches orchestrate stem-cell hierarchy and immune tolerance.
Furuhashi K, Kakiuchi M, Ueda R, Oda H, Ummarino S, Ebralidze AK, Bassal MA, Meng C, Sato T, Lyu J, Han MG, Maruyama S, Watanabe Y, Sawa Y, Kato D, Wake H, Reizis B, Frangos JA, Owens DM, Tenen DG, Ghiran IC, Robson SC, Fujisaki J. Furuhashi K, et al. Among authors: kakiuchi m. Nature. 2025 Jan 1. doi: 10.1038/s41586-024-08352-6. Online ahead of print. Nature. 2025. PMID: 39743593
Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma.
Kakiuchi M, Nishizawa T, Ueda H, Gotoh K, Tanaka A, Hayashi A, Yamamoto S, Tatsuno K, Katoh H, Watanabe Y, Ichimura T, Ushiku T, Funahashi S, Tateishi K, Wada I, Shimizu N, Nomura S, Koike K, Seto Y, Fukayama M, Aburatani H, Ishikawa S. Kakiuchi M, et al. Nat Genet. 2014 Jun;46(6):583-7. doi: 10.1038/ng.2984. Epub 2014 May 11. Nat Genet. 2014. PMID: 24816255
Deletion of Histone Methyltransferase G9a Suppresses Mutant Kras-driven Pancreatic Carcinogenesis.
Kato H, Tateishi K, Fujiwara H, Ijichi H, Yamamoto K, Nakatsuka T, Kakiuchi M, Sano M, Kudo Y, Hayakawa Y, Nakagawa H, Tanaka Y, Otsuka M, Hirata Y, Tachibana M, Shinkai Y, Koike K. Kato H, et al. Among authors: kakiuchi m. Cancer Genomics Proteomics. 2020 Nov-Dec;17(6):695-705. doi: 10.21873/cgp.20224. Cancer Genomics Proteomics. 2020. PMID: 33099471 Free PMC article.
Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.
Soeda K, Sasako T, Enooku K, Kubota N, Kobayashi N, Ikushima YM, Awazawa M, Bouchi R, Toda G, Yamada T, Nakatsuka T, Tateishi R, Kakiuchi M, Yamamoto S, Tatsuno K, Atarashi K, Suda W, Honda K, Aburatani H, Yamauchi T, Fujishiro M, Noda T, Koike K, Kadowaki T, Ueki K. Soeda K, et al. Among authors: kakiuchi m. Nat Commun. 2023 Oct 18;14(1):6584. doi: 10.1038/s41467-023-42334-y. Nat Commun. 2023. PMID: 37852976 Free PMC article.
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