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Mendelian neurodegenerative disease genes involved in autophagy.
Stamatakou E, Wróbel L, Hill SM, Puri C, Son SM, Fujimaki M, Zhu Y, Siddiqi F, Fernandez-Estevez M, Manni MM, Park SJ, Villeneuve J, Rubinsztein DC. Stamatakou E, et al. Among authors: hill sm. Cell Discov. 2020 May 5;6:24. doi: 10.1038/s41421-020-0158-y. eCollection 2020. Cell Discov. 2020. PMID: 32377374 Free PMC article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 33947844
VCP/p97 regulates Beclin-1-dependent autophagy initiation.
Hill SM, Wrobel L, Ashkenazi A, Fernandez-Estevez M, Tan K, Bürli RW, Rubinsztein DC. Hill SM, et al. Nat Chem Biol. 2021 Apr;17(4):448-455. doi: 10.1038/s41589-020-00726-x. Epub 2021 Jan 28. Nat Chem Biol. 2021. PMID: 33510452
VCP/p97 modulates PtdIns3P production and autophagy initiation.
Wrobel L, Hill SM, Ashkenazi A, Rubinsztein DC. Wrobel L, et al. Among authors: hill sm. Autophagy. 2021 Apr;17(4):1052-1053. doi: 10.1080/15548627.2021.1898742. Epub 2021 Mar 9. Autophagy. 2021. PMID: 33719912 Free PMC article.
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.
Wrobel L, Hill SM, Djajadikerta A, Fernandez-Estevez M, Karabiyik C, Ashkenazi A, Barratt VJ, Stamatakou E, Gunnarsson A, Rasmusson T, Miele EW, Beaton N, Bruderer R, Feng Y, Reiter L, Castaldi MP, Jarvis R, Tan K, Bürli RW, Rubinsztein DC. Wrobel L, et al. Among authors: hill sm. Nat Commun. 2022 Jul 16;13(1):4146. doi: 10.1038/s41467-022-31905-0. Nat Commun. 2022. PMID: 35842429 Free PMC article.
200 results